F3800

Sigma-Aldrich

4-Fluoroaniline

99%

Synonym(s):
1-Amino-4-fluorobenzene
Linear Formula:
FC6H4NH2
CAS Number:
Molecular Weight:
111.12
Beilstein/REAXYS Number:
742030
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

assay

99%

refractive index

n20/D 1.539 (lit.)

bp

187 °C/767 mmHg (lit.)

density

1.173 g/mL at 25 °C (lit.)

SMILES string

Nc1ccc(F)cc1

InChI

1S/C6H6FN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2

InChI key

KRZCOLNOCZKSDF-UHFFFAOYSA-N

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Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 2941 6.1 / PGIII

WGK Germany

WGK 1

C V Eadsforth et al.
Xenobiotica; the fate of foreign compounds in biological systems, 16(6), 555-566 (1986-06-01)
o-Fluoroaniline is rapidly metabolized and excreted in rats, rabbits and marmosets. Following a single oral dose of 14C-fluoroaniline of about 20 mg/kg, more than 80% of the dose is excreted in 0-24 h, the urine being the major route of...
Meizhen Wang et al.
Environmental science and pollution research international, 20(9), 6201-6209 (2013-04-17)
To develop a bacterial bioaugmentation system for fluorine-containing industrial wastewater treatment, optimal conditions for 4-fluoroaniline (4-FA) degradation and autoinducer release in Acinetobacter sp. TW were determined. Quorum sensing in biofilms of strain TW was also investigated. Different optimal conditions exist...
G B Scarfe et al.
Xenobiotica; the fate of foreign compounds in biological systems, 29(2), 205-216 (1999-04-13)
1. The urinary metabolic fate of 4-fluoroaniline (4-FA) and 1-[13C]-4-fluoroacetanilide (4-FAA) has been studied using NMR-based methods after 50 and 100 mg kg(-1) i.p. doses respectively to the male Sprague-Dawley rat. 2. 4-FA was both ortho- and para-hydroxylated. The major...
I M Rietjens et al.
Chemico-biological interactions, 77(3), 263-281 (1991-01-01)
Metabolism and bioactivation of fluoroanilines was studied both in vitro in microsomal systems and in vivo. 4-Fluoroaniline and pentafluoroaniline and their non-para fluorinated analogues were used as the model compounds. Special attention was focussed on bioactivation to reactive benzoquinoneimines. Cytochrome...
J G Bundy et al.
Xenobiotica; the fate of foreign compounds in biological systems, 32(6), 479-490 (2002-08-06)
1. Little is known about metabolism of xenobiotics by earthworms, despite their importance in soil ecotoxicity testing. Normal earthworms and earthworms treated with antibiotics to ensure inhibition of gut microflora were exposed to two model xenobiotic compounds, 4-fluoroaniline and 4-fluorobiphenyl...

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