G10806

Gramine

99%

• Synonym(s): 3-(Dimethylaminomethyl)indole, Donaxine, NSC 16892
• Empirical Formula (Hill Notation): C₁₁H₁₄N₂
• CAS Number: 87-52-5
• Molecular Weight: 174.24
• Beilstein: 140521
• EC Number: 201-749-8
• MDL number: MFCD00005629
• PubChem Substance ID: 24895037
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 99%
• mp: 132-134 °C (lit.)
• SMILES string: CN(C)Cc1c[nH]c2ccccc12
• InChI: 1S/C11H14N2/c1-13(2)8-9-7-12-11-6-4-3-5-10(9)11/h3-7,12H,8H2,1-2H3
• InChI key: OCDGBSUVYYVKQZ-UHFFFAOYSA-N

Description

Application

Reactant for preparation of:

• Dopamine D2 receptor antagonists
• Anti-malarial drugs
• 5-indolyl-Mannich bases
• Proliferation inhibitors
• Inhibitors of human mast cell chymase
• Preparation of DL-tryptophan
• Potential detoxification inhibitors of the crucifer phytoalexin brassinin
• 3-vinylindoles
• Serotonin 5-HT6 receptor ligand templates
• Selective protein kinase c delta (PKCδ) down regulators

Packaging

25, 100, 500 g

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 + H312
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P302 + P352 + P312 - P362 + P364
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 332.6 °F
• Flash Point(C): 167 °C