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H6377

Sigma-Aldrich

1-Hydroxypyridine-2-thione zinc salt

≥95%

Synonym(s):
Pyrithione, Mercaptopyridine N-oxide zinc salt
Empirical Formula (Hill Notation):
C10H8N2O2S2Zn
CAS Number:
Molecular Weight:
317.70
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥95%

SMILES string

O1N2C=CC=CC2=[S][Zn]13ON4C=CC=CC4=[S]3

InChI

1S/2C5H5NOS.Zn/c2*7-6-4-2-1-3-5(6)8;/h2*1-4,8H;/q;;+2/p-2

InChI key

OTPSWLRZXRHDNX-UHFFFAOYSA-L

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Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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More documents

Quotes and Ordering

Nancy L Reeder et al.
Antimicrobial agents and chemotherapy, 55(12), 5753-5760 (2011-09-29)
Zinc pyrithione (ZPT) is an antimicrobial material with widespread use in antidandruff shampoos and antifouling paints. Despite decades of commercial use, there is little understanding of its antimicrobial mechanism of action. We used a combination of genome-wide approaches (yeast deletion
Kathy Kerr et al.
Acta dermato-venereologica, 91(4), 404-408 (2011-02-22)
Dandruff and seborrhoeic dermatitis are accompanied by bothersome itch. We have established a novel non-invasive methodology to sample histamine levels in the stratum corneum in order to facilitate an understanding of pruritogenesis in this condition. Histamine levels were assessed in
N L Reeder et al.
The British journal of dermatology, 165 Suppl 2, 9-12 (2011-09-23)
Zinc pyrithione (ZPT) is the active ingredient most commonly used in many antidandruff treatments. Despite decades of successful use to treat human scalps, little is understood about the antifungal mechanism of action of ZPT. The objective of this study is
Emil Rudolf et al.
Toxicology letters, 204(2-3), 164-173 (2011-05-12)
Zinc pyrithione is used as a topical agent in a range of medicinal and cosmetic applications. Despite its extensive use and reported beneficial effects in treatment of various dermal problems, its potential toxicity towards skin cells remains relatively underexplored. In
Marco Marcheselli et al.
Aquatic toxicology (Amsterdam, Netherlands), 102(1-2), 39-47 (2011-03-05)
The anti-fouling biocide zinc pyrithione (ZnPT) was recently demonstrated to be more persistent than expected in the coastal environment, and to have a potential for bioaccumulation. We investigated the occurrence of adverse effects in the marine mussel Mytilus galloprovincialis when

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