I10406

Sigma-Aldrich

Iodonitrotetrazolium chloride

95%

Synonym(s):
2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride, p-Iodonitrotetrazolium Violet, INT
Empirical Formula (Hill Notation):
C19H13ClIN5O2
CAS Number:
Molecular Weight:
505.70
Beilstein/REAXYS Number:
4093224
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

95%

impurities

<5% methyl alcohol

mp

240 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

[Cl-].[O-][N+](=O)c1ccc(cc1)-[n+]2nc(nn2-c3ccc(I)cc3)-c4ccccc4

InChI

1S/C19H13IN5O2.ClH/c20-15-6-8-16(9-7-15)23-21-19(14-4-2-1-3-5-14)22-24(23)17-10-12-18(13-11-17)25(26)27;/h1-13H;1H/q+1;/p-1

InChI key

JORABGDXCIBAFL-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

Application

Iodonitrotetrazolium chloride (INT) on reduction gets converted to iodonitrotetrazolium formazan, a water insoluble violet colored dye or indicator. Hence INT can be used for the colorimetric assay of various dehydrogenases.
Electron acceptor for the colorimetric assay of various dehydrogenases

Packaging

5 g in glass bottle
25 g in poly bottle
1 g in poly bottle

Signal Word

Danger

Hazard Statements

hazcat

Flam. Sol. 1 - STOT SE 2 - STOT SE 3

Target Organs

Respiratory system

storage_class_code

4.1B - Flammable solid hazardous materials

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

The role of glycerol in the nutrition of halophilic archaeal communities: a study of respiratory electron transport
Oren A
FEMS Microbiology Ecology, 16(4), 281-290 (1995)
E G Pearson
Journal of the American Veterinary Medical Association, 198(9), 1651-1654 (1991-05-01)
Of 41 equids referred to a veterinary teaching hospital in the Pacific northwest because of dyspnea and inspiratory noise, 3 ponies were diagnosed as having liver failure, most likely attributable to pyrrolizidine alkaloid toxicosis. Dyspnea appeared to be caused by...
The measurement of electron transport system activity in river biofilms
Blenkinsopp SA and Lock MA
Water Research, 24(4), 441-445 (1990)
The role of cysteine residues of spinach ferredoxin-NADP+ reductase as assessed by site-directed mutagenesis
Aliverti A, et al.
Biochemistry, 32(25), 6374-6380 (1993)
Xing Jun Li et al.
Journal of leukocyte biology, 81(1), 238-249 (2006-10-25)
The role of Leu505 of Nox2 on the NADPH oxidase activation process was investigated. An X-CGD PLB-985 cell line expressing the Leu505Arg Nox2 mutant was obtained, exactly mimicking the phenotype of a previously published X91+-CGD case. In a reconstituted cell-free...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service