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K6000

Sigma-Aldrich

α-Keto-γ-(methylthio)butyric acid sodium salt

≥97%

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Synonym(s):
4-Methylthio-2-oxobutanoic acid sodium salt, 4-Methylthio-2-oxobutyric acid sodium salt, KMBA
Linear Formula:
C5H7O3SNa
CAS Number:
Molecular Weight:
170.16
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥97%

storage temp.

2-8°C

SMILES string

[Na].CSCCC(=O)C(O)=O

InChI

1S/C5H8O3S.Na/c1-9-3-2-4(6)5(7)8;/h2-3H2,1H3,(H,7,8);/q;+1/p-1

InChI key

IFSCKRWNXKWTLR-UHFFFAOYSA-M

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1 of 4

This Item
K662594904K0875
2-Ketohexanoic acid sodium salt 97.0-103.0%

K6625

2-Ketohexanoic acid sodium salt

Sodium 4-vinylbenzenesulfonate technical, ≥90% (T)

94904

Sodium 4-vinylbenzenesulfonate

Sodium 2-oxobutyrate powder

K0875

Sodium 2-oxobutyrate

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Baiqing Tang et al.
Biochemical pharmacology, 72(7), 806-815 (2006-07-28)
4-Methylthio-2-oxobutanoic acid (MTOB) is the final compound of the methionine salvage pathway that converts the polyamine byproduct methylthioadenosine to adenine and methionine. Here we find that MTOB inhibits growth of several human cell lines in a dose-dependent manner. Growth inhibition
Y Dai et al.
The Journal of biological chemistry, 274(3), 1193-1195 (1999-01-09)
Two enzymes, designated, E-2 and E-2', catalyze different oxidation reactions of an aci-reductone intermediate in the methionine salvage pathway. E-2 and E-2', overproduced in Escherichia coli from the same gene, have the same protein component. E-2 and E-2' are separable
Kimberly L Falk et al.
Phytochemistry, 65(8), 1073-1084 (2004-04-28)
Glucosinolates are a group of sulfur-rich thioglucoside natural products common in the Brassicaceae and related plant families. The first phase in the formation of many glucosinolates involves the chain extension of the amino acid methionine. Additional methylene groups are inserted
H Schempp et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 13 Suppl 5, 36-44 (2006-06-17)
A combination of ethanolic extracts from nine medicinal plants is successfully used in STW 5 (Iberogast((R))) for treatment of gastrointestinal disorders. To elucidate possible modes of action, the focus of this study is on antioxidant properties of the phytomedicine STW
D R Livingstone et al.
Marine environmental research, 50(1-5), 57-60 (2001-07-20)
The present study investigated the proposed involvement of contaminant-stimulated reactive oxygen species (ROS) production in disease processes in fish. NAD(P)H-dependent ROS production of subcellular fractions was determined by the iron/EDTA-mediated oxidation of 2-keto-4-methiolbutyric acid. Hepatic cytosolic NADPH-dependent and microsomal NAD(P)H-dependent

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