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M10050

Sigma-Aldrich

3-Methoxybenzamide

97%

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Synonym(s):
m-Anisamide
Linear Formula:
CH3OC6H4CONH2
CAS Number:
Molecular Weight:
151.16
Beilstein/REAXYS Number:
2206857
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

assay

97%

mp

132.5-135.5 °C (lit.)

SMILES string

COc1cccc(c1)C(N)=O

InChI

1S/C8H9NO2/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5H,1H3,(H2,9,10)

InChI key

VKPLPDIMEREJJF-UHFFFAOYSA-N

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Show Differences

1 of 4

This Item
154261M10069630934
vibrant-m

M10050

3-Methoxybenzamide

vibrant-m

154261

4-Bromo-3-methylaniline

vibrant-m

M10069

4-Methoxybenzamide

vibrant-m

630934

3-Methoxy-N-methylaniline

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

mp

132.5-135.5 °C (lit.)

mp

80-82 °C (lit.)

mp

164-167 °C (lit.)

mp

-

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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R C Tasker et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 18(12), 1346-1356 (1998-12-16)
In the infant brain, ischemia-induced ionic and enzyme mechanisms may independently lead to cell death by energy depletion: resequestration of calcium mobilized from intracellular stores consumes ATP, and activated poly(ADP-ribose) polymerase (PARP) uses oxidized nicotinamide adenine dinucleotide to form polyADP-ribosyl
Neil R Stokes et al.
Antimicrobial agents and chemotherapy, 57(1), 317-325 (2012-11-02)
The bacterial cell division protein FtsZ is an attractive target for small-molecule antibacterial drug discovery. Derivatives of 3-methoxybenzamide, including compound PC190723, have been reported to be potent and selective antistaphylococcal agents which exert their effects through the disruption of intracellular
B C Waldman et al.
Nucleic acids research, 18(20), 5981-5988 (1990-10-25)
We determined the effect of 3-methoxybenzamide (3-MB), a competitive inhibitor of poly(ADP-ribose)polymerase (E.C. 2.4.2.30), on illegitimate and extrachromosomal homologous recombination in mouse Ltk- cells. Cells were transfected with a wild type Herpes thymidine kinase (tk) gene or with two defective
H Y Dong et al.
Mutation research, 331(2), 197-204 (1995-10-01)
To investigate the origin of DNA repair in rat pleural mesothelial cells (RPMC) exposed to asbestos fibers, poly(ADP-ribose) polymerase (PARP) activity was measured in the asbestos-treated cells. As bleomycin has been shown to activate poly(ADP-ribose) synthesis in several cell systems
S Hauschildt et al.
Advances in experimental medicine and biology, 419, 249-252 (1997-01-01)
Stimulating monocytes/macrophages with bacterial lipopolysaccharide (LPS) results in TNF-alpha, IL-1, IL-6 and nitrite (NO2-) formation. Inhibitors of poly(ADP-ribose)polymerase inhibit release of these mediators by preventing mRNA expression indicating that ADP-ribosylation plays a crucial role in the synthesis of these mediators.

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