M1381

4-Methylumbelliferone

≥98%

• Synonym(s): β-Methylumbelliferone, 4-MU, 7-Hydroxy-4-methylcoumarin
• Empirical Formula (Hill Notation): C₁₀H₈O₃
• CAS Number: 90-33-5
• Molecular Weight: 176.17
• Beilstein: 142217
• EC Number: 201-986-7
• MDL number: MFCD00006866
• PubChem Substance ID: 57654353
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: ≥98%
• color: off-white to yellow
• fluorescence: λ_ex 372 nm; λ_em 445 nm in ethanol
• SMILES string: CC1=CC(=O)Oc2cc(O)ccc12
• InChI: 1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3
• InChI key: HSHNITRMYYLLCV-UHFFFAOYSA-N

Description

Application

4-Methylumbelliferone is primarily used in synthesizing medicinal compounds and as a building block for fluorescent probes. Applications include synthesis of:

• coumarin triazole derivatives as potential antimicrobial agents.
• coumarin salen-based fluorescence sensors for Mg²⁺ detection.
• pyranocoumarin derivatives as anti-hyperglycemic and anti-dyslipidemic agents.
• coumarin piperazine derivatives as potential multireceptor atypical antipsychotics.
• 4-methylumbelliferyl T-antigen as a substrate for endo-α-N-acetylgalactosaminidase.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves