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M6204

Sigma-Aldrich

2-Thiazoline-2-thiol

98%

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Synonym(s):
2-Mercapto-2-thiazoline
Empirical Formula (Hill Notation):
C3H5NS2
CAS Number:
Molecular Weight:
119.21
Beilstein:
106332
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

mp

100-105 °C (lit.)

SMILES string

S=C1NCCS1

InChI

1S/C3H5NS2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)

InChI key

WGJCBBASTRWVJL-UHFFFAOYSA-N

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1 of 4

This Item
250406F204088.21111
2-Thiazoline-2-thiol 98%

Sigma-Aldrich

M6204

2-Thiazoline-2-thiol

2-Furanmethanethiol 98%

Sigma-Aldrich

F20408

2-Furanmethanethiol

2-Thiazoline-2-thiol for synthesis

Sigma-Aldrich

8.21111

2-Thiazoline-2-thiol

mp

100-105 °C (lit.)

mp

-

mp

-

mp

101-106 °C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

Application

Tool for highly selective chiral syntheses of penam- and carbapenam-type β-lactam antibiotics.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Stud. Org. Chem., 28, 57-57 (1987)
Cestmír Konák et al.
Langmuir : the ACS journal of surfaces and colloids, 24(14), 7092-7098 (2008-06-12)
Vesicles bearing either cationic (amino) groups or zwitterionic (amino acid) groups on the surface were coated with a reactive multivalent hydrophilic N-(2-hydroxypropyl)methacrylamide polymer (PHPMA) and its positively charged analogue (3 mol % quaternary ammonium groups), both having reactive thiazolidine-2-thione (TT)
J C Thomes et al.
Japanese journal of pharmacology, 58(3), 201-207 (1992-03-01)
2-Thiazoline-2-thiol is an antithyroid agent that strongly reduces thyroid hormone levels. Synthesis of these hormones is catalyzed in vivo by thyroid peroxidase. The interaction of this drug with molecular iodine and its effect on peroxidase activity were investigated. Iodine and
Vladimír Subr et al.
Biomacromolecules, 7(1), 122-130 (2006-01-10)
N-(2-Hydroxypropyl)methacrylamide (HPMA) copolymers (pHPMA) containing 4-nitrophenyl ester (ONp) or thiazolidine-2-thione (TT) reactive groups in side chains and telechelic/semitelechelic pHPMA with TT groups were designed as highly hydrophilic biocompatible polymers suitable for chemical coating of polyelectrolyte-based DNA-containing nanoparticles bearing amino groups
Arash Nanbakhsh et al.
Blood, 123(23), 3585-3595 (2014-03-29)
Cytarabine (cytosine arabinoside) is one of the most effective drugs for the treatment of patients diagnosed with acute myeloid leukemia (AML). Despite its efficiency against AML cells, the emergence of drug resistance due to prolonged chemotherapy in most patients is

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