M6204
2-Thiazoline-2-thiol
98%
Synonym(s):
2-Mercapto-2-thiazoline
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About This Item
Empirical Formula (Hill Notation):
C3H5NS2
CAS Number:
Molecular Weight:
119.21
Beilstein/REAXYS Number:
106332
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
98%
mp
100-105 °C (lit.)
SMILES string
S=C1NCCS1
InChI
1S/C3H5NS2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
InChI key
WGJCBBASTRWVJL-UHFFFAOYSA-N
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Application
Tool for highly selective chiral syntheses of penam- and carbapenam-type β-lactam antibiotics.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Stud. Org. Chem., 28, 57-57 (1987)
Cestmír Konák et al.
Langmuir : the ACS journal of surfaces and colloids, 24(14), 7092-7098 (2008-06-12)
Vesicles bearing either cationic (amino) groups or zwitterionic (amino acid) groups on the surface were coated with a reactive multivalent hydrophilic N-(2-hydroxypropyl)methacrylamide polymer (PHPMA) and its positively charged analogue (3 mol % quaternary ammonium groups), both having reactive thiazolidine-2-thione (TT)
Taro Hase et al.
Urology, 60(3), 542-547 (2002-09-28)
To investigate the expression of peroxisome proliferator activator-receptor (PPAR)-alpha, beta, and gamma in human testicular cancer (TC) and normal testicular (NT) tissues, as well as the effects of the PPAR-gamma ligand. Recent studies have demonstrated that PPAR-gamma is expressed in
J C Thomes et al.
Japanese journal of pharmacology, 58(3), 201-207 (1992-03-01)
2-Thiazoline-2-thiol is an antithyroid agent that strongly reduces thyroid hormone levels. Synthesis of these hormones is catalyzed in vivo by thyroid peroxidase. The interaction of this drug with molecular iodine and its effect on peroxidase activity were investigated. Iodine and
R B Greenwald et al.
Bioconjugate chemistry, 7(6), 638-641 (1996-11-01)
A novel PEG linker that employs a thiazolidine-2-thione group has been synthesized. Kinetic studies done on this compound demonstrate a relatively long half-life compared to those of traditional succinimidyl linkers. This new PEG derivative reacts with proteins under mild conditions
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