OCNIAK05

Sigma-Aldrich

SMCC Conjugation Kit for Iron Oxide (III) Nanoparticles

5 nm, amine functionalized, 5 mg/mL

form

nanoparticles

concentration

5 mg/mL

particle size

5 nm

functional group

amine

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Application

Iron oxide nanoparticles are magnetic single crystals and can be used as magnetic resonance imaging contrast reagents for in-vivo imaging , drug delivery vehicle, hyperthermia genertor for therapy, adjuvant for vaccine, and magnetic sensing probe for in-vitro diagnostics. These amine terminated iron oxide nanocrystals of various diameters (10 nm-30 nm) are now available in an easy-to-use kit format to enable researchers to conjugate proteins/ligands of their own choice to these iron oxide nanoparticles. The kit is used to specifically conjugate iron oxide nanoparticles and thiol containing ligands with low non-specific binding. It contains sufficient reagents & components for performing 5 conjugation reactions using 1 mg iron oxide nanoparticles per reaction. The iron oxide nanoparticles are activated using SMCC (succinimidyl 4-(N-maleimidomethyl) cyclohexane-1-carboxylate) followed by conjugation to thiol groups that are present on the target protein/ligands such as bovine serum albumin, streptavidin and immunoglobulin.

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Product of Ocean Nanotech, LLC.

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