P60205

Sigma-Aldrich

2-Pyridinealdoxime methiodide

99%

Synonym(s):
Pralidoxime iodide, 2-PAM iodide, 2-PAM
Empirical Formula (Hill Notation):
C7H11IN2O
CAS Number:
Molecular Weight:
266.08
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99%

mp

220 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

[I-].C[n+]1ccccc1\C=N\O

InChI

1S/C7H8N2O.HI/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H

InChI key

QNBVYCDYFJUNLO-UHFFFAOYSA-N

Gene Information

human ... ACHE(43)

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Kimberly D Spradling et al.
Journal of neuroinflammation, 8, 83-83 (2011-07-23)
Organophosphorus nerve agents irreversibly inhibit acetylcholinesterase, causing a toxic buildup of acetylcholine at muscarinic and nicotinic receptors. Current medical countermeasures to nerve agent intoxication increase survival if administered within a short period of time following exposure but may not fully...
Pavel Škaloud et al.
Journal of phycology, 56(3), 574-591 (2020-02-18)
We performed a comparison of molecular and morphological diversity in a freshwater colonial genus Synura (Chrysophyceae, Stramenopiles), using the island of Newfoundland (Canada) as a case study. We examined the morphological species diversity in collections from 79 localities, and compared...
Kazuhito Nomura et al.
Scientific reports, 10(1), 15834-15834 (2020-09-29)
Whether central apnoea or hypopnoea can be induced by organophosphorus poisoning remains unknown to date. By using the acute brainstem slice method and multi-electrode array system, we established a paraoxon (a typical acetylcholinesterase inhibitor) poisoning model to investigate the time-dependent...
Lorise C Gahring et al.
American journal of physiology. Lung cellular and molecular physiology, 319(4), L683-L692 (2020-07-30)
Nicotine of unprecedented concentrations and purity is being inhaled by those using commercially available electronic nicotine delivery systems (ENDS). The consequences of this route of self-administration on the immunological response to inhaled allergens are not known. In mice, sensitization and...
Kimberly D Spradling et al.
Journal of neuroinflammation, 8, 84-84 (2011-07-23)
Although the acute toxicity of organophosphorus nerve agents is known to result from acetylcholinesterase inhibition, the molecular mechanisms involved in the development of neuropathology following nerve agent-induced seizure are not well understood. To help determine these pathways, we previously used...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.