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P74370

Sigma-Aldrich

2-Pyrrolidinone

99%

Synonym(s):
2-Pyrrolidone, Butyrolactam
Empirical Formula (Hill Notation):
C4H7NO
CAS Number:
Molecular Weight:
85.10
Beilstein:
105241
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

vapor density

2.9 (vs air)

assay

99%

form

solid

refractive index

n20/D 1.487 (lit.)

bp

245 °C (lit.)

mp

23-25 °C (lit.)

solubility

H2O: miscible (completely)

density

1.12 g/mL at 25 °C (lit.)

SMILES string

O=C1CCCN1

InChI

1S/C4H7NO/c6-4-2-1-3-5-4/h1-3H2,(H,5,6)

InChI key

HNJBEVLQSNELDL-UHFFFAOYSA-N

Gene Information

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Application

2-Pyrrolidinone is a γ-lactam that can undergo copolymerization with other lactams to form polyamides.

Packaging

20 kg in steel drum
25, 500 g in glass bottle
1 kg in glass bottle

Pictograms

Exclamation markHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Repr. 1B

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

13C?NMR sequence analysis. 19. Anionic copolymerization of ??butyrolactam, ??valerolactam, and caprolactam at low temperatures.
Kricheldorf H R, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 20(9), 2353-2370 (1982)
Anionic copolymerization of lactams.
Kricheldorf H R, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 16(9), 2253-2264 (1978)
M Göbbels et al.
Ophthalmology, 99(6), 873-878 (1992-06-01)
The question of whether artificial tears can lead to objective improvement of ocular surface disease in dry eyes is still unanswered. The aim of the current study is to assess the influence of artificial tears on corneal epithelial permeability of
Toshiyuki Matsudo et al.
Biomacromolecules, 4(6), 1794-1799 (2003-11-11)
The formation of protein-polymer complexes was studied in an aqueous system using dynamic light scattering (DLS) and static light scattering (SLS) as the main experimental tools. Human serum albumin (HSA) was used as a protein and complexed with four representative
Gunasekar Ramachandran et al.
Organic & biomolecular chemistry, 10(28), 5343-5346 (2012-06-15)
A simple and efficient three components domino reaction of γ-butyrolactam (2-pyrrolidinone), aromatic aldehyde and substituted thiophenol catalyzed by elemental iodine resulted in the formation of 1-((phenylthio)(phenyl)methyl)pyrrolidin-2-one derivatives. The stability of the synthesized analogues was evaluated in stimulated gastric fluid (SGF)

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