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QBD10175

Sigma-Aldrich

m-dPEG®4-amine

Synonym(s):
2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethylamine, 3,6,9,12-Tetraoxatridecylamine, Triethylene glycol 2-aminoethyl methyl ether
Empirical Formula (Hill Notation):
C9H21NO4
CAS Number:
Molecular Weight:
207.27
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: carboxyl reactive

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

NCCOCCOCCOCCOC

InChI

1S/C9H21NO4/c1-11-4-5-13-8-9-14-7-6-12-3-2-10/h2-10H2,1H3

InChI key

DQTQYVYXIOQYGN-UHFFFAOYSA-N

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m-dPEG®4-amine

Sigma-Aldrich

QBD10175

m-dPEG®4-amine

m-dPEG®4-NHS ester

Sigma-Aldrich

QBD10211

m-dPEG®4-NHS ester

m-dPEG®8-amine

Sigma-Aldrich

QBD10278

m-dPEG®8-amine

Amino-dPEG®4-OH

Sigma-Aldrich

QBD10249

Amino-dPEG®4-OH

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent, reagent type: cross-linking reagent
reactivity: carboxyl reactive

reaction suitability

reagent type: chemical modification reagent, reagent type: cross-linking reagent
reactivity: amine reactive

reaction suitability

reagent type: chemical modification reagent, reagent type: cross-linking reagent
reactivity: carboxyl reactive

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

polymer architecture

shape: linear
functionality: monofunctional

polymer architecture

shape: linear
functionality: monofunctional

polymer architecture

shape: linear
functionality: monofunctional

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Features and Benefits

m-dPEG®4-amine provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG® molecules are hydrophilic and non-immunogenic of exact length. There are four repeat units in this linear dPEG® chain. Modification with m-dPEG® reagent can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®4-amine reacts with carboxylic acids and active esters.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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