This product contains only the dPEG4 polymer length and does not include other PEG derivative lengths, such as PEG 3 or PEG 5 isomers. Therefore, there are no additional PEG monomer lengths present in this product.
QBD10200
NHS-dPEG®4-biotin
Synonym(s):
(+)-Biotin-PEO4-NHS-propionate, NHS-PEO4-Biotin, Polyethylene glycol
Sign Into View Organizational & Contract Pricing
Select a Size
50 MG
$168.00
1000 MG
$1,090.00
All Photos(1)
Select a Size
Change View
50 MG
$168.00
1000 MG
$1,090.00
About This Item
Empirical Formula (Hill Notation):
C25H40N4O10S
CAS Number:
Molecular Weight:
588.67
UNSPSC Code:
12161502
PubChem Substance ID:
NACRES:
NA.22
assay
>90%
form
solid or viscous liquid
reaction suitability
reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: amine reactive
reagent type: linker
polymer architecture
shape: linear
functionality: monofunctional
shipped in
ambient
storage temp.
−20°C
SMILES string
O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCNC(CCCCC2C3NC(NC3CS2)=O)=O
InChI
1S/C25H40N4O10S/c30-20(4-2-1-3-19-24-18(17-40-19)27-25(34)28-24)26-8-10-36-12-14-38-16-15-37-13-11-35-9-7-23(33)39-29-21(31)5-6-22(29)32/h18-19,24H,1-17H2,(H,26,30)(H2,27,28,34)/t18-,19-,24-/m0/s1
InChI key
DTLVBHCSSNJCMJ-JXQFQVJHSA-N
Related Categories
1 of 4
This Item | QBD10774 | QBD10198 | QBD10203 |
|---|---|---|---|
| assay >90% | assay >90% | assay >90% | assay >90% |
| form solid or viscous liquid | form solid or viscous liquid | form solid or viscous liquid | form solid or viscous liquid |
| polymer architecture shape: linear | polymer architecture shape: linear | polymer architecture shape: linear | polymer architecture shape: linear |
| reaction suitability reagent type: cross-linking reagent | reaction suitability - | reaction suitability reagent type: cross-linking reagent | reaction suitability reagent type: cross-linking reagent |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| shipped in ambient | shipped in ambient | shipped in ambient | shipped in ambient |
General description
NHS-dPEG®4-biotin is a water-soluble cross-linking reagent used in biotinylation reactions. The N-hydroxysuccinimidyl (NHS) moiety of NHS-dPEG®4-biotin forms a stable amide bond with free primary amines, such as the amines on the side chain of lysine. The biotin moiety is used in a variety of applications, including labeling, supramolecular building, affinity chromatography, pull-down assays, and the production of biotinylated antibodies.[1]
Features and Benefits
NHS-dPEG®4-biotin is used extensively to label molecules that contain a free amine with biotin. The single molecular weight NHS-dPEG®4-biotin has a long spacer of precise length (19.2 Å) between the biotin moiety and the labeled molecule. This dPEG® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.
If you need assistance, please contact Customer Support
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
-
Are there other peg derivative lengths present beside the dPEG4 polymer length in the product? For example, are there PEG 3 or PEG5 isomers? If other peg monomer lengths are present, what is the general percent amount present?
1 answer-
Helpful?
-
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
