QBD10501

Sigma-Aldrich

Azido-dPEG®4-NHS ester

Empirical Formula (Hill Notation):
C15H24N4O8
CAS Number:
Molecular Weight:
388.37
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

assay

>90%

form

solid or viscous liquid

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(CCOCCOCCOCCOCCN=[N+]=[N-])ON1C(CCC1=O)=O

Features and Benefits

The azido-dPEG®4-NHS ester contains an azide function on one end of a single molecular weight dPEG® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. NHS ester readily reacts with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

RIDADR

NONH for all modes of transport

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin

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