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MilliporeSigma

QBD10513

Sigma-Aldrich

Azido-dPEG®12-acid

Synonym(s):

Polyethylene glycol, alpha-(2-azidoethyl)-omega-(2-carboxyethoxy)poly(oxy-1,2-ethanediyl)

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About This Item

Empirical Formula (Hill Notation):
C27H53N3O14
CAS Number:
Molecular Weight:
643.72
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

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assay

>90%

form

solid or viscous liquid

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

InChI

1S/C27H53N3O14/c28-30-29-2-4-34-6-8-36-10-12-38-14-16-40-18-20-42-22-24-44-26-25-43-23-21-41-19-17-39-15-13-37-11-9-35-7-5-33-3-1-27(31)32/h1-26H2,(H,31,32)

InChI key

DYFODOGACDHUBQ-UHFFFAOYSA-N

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1 of 4

This Item
QBD10502QBD10514QBD10512
polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

assay

>90%

assay

>90%

assay

>90%

assay

>90%

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

Features and Benefits

The azido-dPEG®12 contains an azide function on one end of a single molecular weight dPEG® spacer (46.4 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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