QBD10593

DBCO-dPEG ^®₁₂-MAL

Name: DBCO-dPEG <SUP>®</SUP><SUB>12</SUB>-MAL
Brand: ALDRICH
Price: 391 USD
Availability: InStock

Synonym(s):

Polyethylene glycol

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$3,400.00

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About This Item

Empirical Formula (Hill Notation):

C₅₂H₇₄N₄O₁₇

Molecular Weight:

1027.16

UNSPSC Code:

51171641

NACRES:

NA.22

Key Documents

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InChI

1S/C52H74N4O17/c57-48(14-18-55-50(59)11-12-51(55)60)54-17-20-63-22-24-65-26-28-67-30-32-69-34-36-71-38-40-73-42-41-72-39-37-70-35-33-68-31-29-66-27-25-64-23-21-62-19-15-49(58)53-16-13-52(61)56-43-46-7-2-1-5-44(46)9-10-45-6-3-4-8-47(45)56/h1-8,11-12H,13-43

InChI key

RSPJSRPEBGDVOY-UHFFFAOYSA-N

SMILES string

O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)NCCC(N2C3=C(C#CC4=C(C2)C=CC=C4)C=CC=C3)=O

assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: cross-linking reagent
reaction type: click chemistry

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

Related Categories

Chemical Biology

Chemical Biology Tools

Click Chemistry Reagents Overview

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Show Differences

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This Item	QBD10596	QBD10594	QBD10525
Sigma-Aldrich QBD10593 DBCO-dPEG ^®₁₂-MAL	Sigma-Aldrich QBD10596 m-dPEG ^®₁₂-DBCO	Sigma-Aldrich QBD10594 DBCO-dPEG ^®₂₄-MAL	Sigma-Aldrich QBD10525 Azido-dPEG^®₂₃-amine
assay >90%	assay >90%	assay >90%	assay >90%
polymer architecture shape: linear functionality: heterobifunctional	polymer architecture shape: linear functionality: monofunctional	polymer architecture shape: linear functionality: heterobifunctional	polymer architecture shape: linear functionality: heterobifunctional
form solid or viscous liquid	form solid or viscous liquid	form solid or viscous liquid	form solid or viscous liquid
reaction suitability reagent type: cross-linking reagent reaction type: click chemistry	reaction suitability reagent type: chemical modification reagent, reagent type: cross-linking reagent reaction type: click chemistry	reaction suitability reagent type: cross-linking reagent reaction type: click chemistry	reaction suitability -
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
shipped in ambient	shipped in ambient	shipped in ambient	shipped in ambient

General description

DBCO-dPEG^®₁₂-MAL is a versatile heterobifunctional cross-linking reagent used in strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. This approach is also known as copper-free click chemistry. The presence of maleimidopropyl (MAL) functional group in the reagent forms a thiol-ether linkage with sulfhydryl groups.

Features and Benefits

DBCO-dPEG^®₁₂-MAL can be used to conjugate two different proteins or an antibody with a payload by using copper-free "click" chemistry with the DBCO and reaction of the maleimide with a free thiol.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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