QBD10644

Sigma-Aldrich

Lipoamido-dPEG®36-TFP ester

>90% (HPLC)

Synonym(s):
Lipoamido-PEG36-TFP ester, TFP-PEG1500-Lipoamide, Lipoamido-PEG-TFP ester
Empirical Formula (Hill Notation):
C89H163F4NO39S2
Molecular Weight:
2011.35

assay

>90% (HPLC)

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

Inchi Code

1S/C89H163F4NO39S2/c90-83-81-84(91)88(93)89(87(83)92)133-86(96)5-8-97-10-12-99-14-16-101-18-20-103-22-24-105-26-28-107-30-32-109-34-36-111-38-40-113-42-44-115-46-48-117-50-52-119-54-56-121-58-60-123-62-64-125-66-68-127-70-72-129-74-76-131-78-79-132-77-75-130-73-71-128-69-67-126-65-63-124-61-59-122-57-55-120-53-51-118-49-47-116-45-43-114-41-39-112-37-35-110-33-31-108-29-27-106-25-23-104-21-19-102-17-15-100-13-11-98-9-7-94-85(95)4-2-1-3-82-6-80-134-135-82/h81-82H,1-80H2,(H,94,95)

InChI key

LDPLLZZGBNGLDH-UHFFFAOYSA-N

Features and Benefits

Lipoamido-dPEG36-TFP ester is a monodispersed, crosslinking PEGylation reagent that joins free amines to metal surfaces. The discrete PEG (dPEG) portion of this crosslinker is comparable to a PEG1500. The single molecular weight, discrete-chain-length polyethylene glycol (dPEG) product consists of alpha-lipoic acid and a 2,3,5,6-tetrafluorophenol (TFP) ester on opposite ends of a 120 atoms-long (136.1 Å) dPEG spacer. The lipoic acid group forms two (2) coordinate covalent bonds (dative bonds) with metal, especially gold and silver. The TFP ester reacts with free amines to form amide bonds. This product has been utilized for sensor development, peptide or protein immobilization on metal surfaces, and the formation of self-assembled monolayers (SAMs).

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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