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QBD10722

Sigma-Aldrich

Hydroxy-dPEG®24-t-butyl ester

>90% (HPLC)

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Synonym(s):
HO-PEG24-CO-Otbu, HO-PEG24-TBE, Hydroxy-PEG-t-butyl ester, Hydroxy-PEG24-t-butyl-ester, PEG1000-t-butyl ester
Empirical Formula (Hill Notation):
C55H110O27
Molecular Weight:
1203.45
MDL number:

assay

>90% (HPLC)

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

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Hydroxy-dPEG®24-t-butyl ester >90% (HPLC)

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t-Boc-N-amido-dPEG®24-acid >95% (HPLC)

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reaction suitability

reaction type: Pegylations

reaction suitability

reaction type: Pegylations

reaction suitability

reaction type: Pegylations

reaction suitability

reaction type: Pegylations

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: Y-shape
functionality: heterobifunctional

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

Features and Benefits

Hydroxy-dPEG24-t-butyl ester is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain, comparable to a polymeric PEG1000. The single molecular weight, discrete-length PEG (dPEG) chain is 86 atoms (88.5 Å) long. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. The tert-butyl ester deprotects with trifluoroacetic acid (TFA), exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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