QBD10746

m-dPEG^®₈-MAL

• Synonym(s): Polyethylene glycol
• Empirical Formula (Hill Notation): C₂₄H₄₂N₂O₁₁
• CAS Number: 1334169-90-2
• Molecular Weight: 534.60
• UNSPSC Code: 51171641
• PubChem Substance ID: 329823947
• NACRES: NA.22
• MDL number: MFCD13185021

Properties

• assay: >90%
• form: solid or viscous liquid
• reaction suitability: reactivity: thiol reactive, reagent type: chemical modification reagent, reagent type: cross-linking reagent; reactivity: sulfhydryl reactive
• polymer architecture: shape: linear; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: COCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O
• InChI: 1S/C24H42N2O11/c1-30-8-9-32-12-13-34-16-17-36-20-21-37-19-18-35-15-14-33-11-10-31-7-5-25-22(27)4-6-26-23(28)2-3-24(26)29/h2-3H,4-21H2,1H3,(H,25,27)
• InChI key: DYKKRMSENAYADQ-UHFFFAOYSA-N

Description

Features and Benefits

The m-dPEG^®₈-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₈-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable