QBD10869

Sigma-Aldrich

Amino-dPEG®36-OH

>95% (HPLC)

Synonym(s):
Amino-PEG36-OH, Hydroxy-PEG36-amine, OH-PEG36-NH2, PEG1500-amine, Hydroxy-PEG-amine
Empirical Formula (Hill Notation):
C72H147NO36
Molecular Weight:
1602.92
MDL number:

assay

>95% (HPLC)

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

Inchi Code

1S/C72H147NO36/c73-1-3-75-5-7-77-9-11-79-13-15-81-17-19-83-21-23-85-25-27-87-29-31-89-33-35-91-37-39-93-41-43-95-45-47-97-49-51-99-53-55-101-57-59-103-61-63-105-65-67-107-69-71-109-72-70-108-68-66-106-64-62-104-60-58-102-56-54-100-52-50-98-48-46-96-44-42-94-40-38-92-36-34-90-32-30-88-28-26-86-24-22-84-20-18-82-16-14-80-12-10-78-8-6-76-4-2-74/h74H,1-73H2

InChI key

MAESJFAEMPPQIN-UHFFFAOYSA-N

Features and Benefits

Amino-dPEG36-OH, also known as Amino-dPEG36-alcohol, is a very long (109 atoms, 127.7 Å) monodispersed PEGylation reagent functionalized with a primary amine on one end of the molecule that reacts with carboxylic acids, aldehydes, and ketones. Reacting the amine group with carboxylic acids yields stable amides while reacting the amine group with aldehydes and ketones forms Schiff bases that are reducible to secondary amines for stability. If needed, various functional and reactive groups can modify the terminal alcohol on the opposite end of the molecule to provide the dPEG product with additional reactivity or crosslinking capability. dPEG36 is a monodisperse equivalent of the polymeric PEG1500. Amino-dPEG36-OH can be used for passivation of carboxylate-functionalized surfaces. The non-immunogenic terminal alcohol of the PEG chain imparts hydrophilicity to the conjugate molecule or surface. Consequently, conjugate molecules are water-soluble.

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.