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QBD11389

Sigma-Aldrich

t-Boc-N-amido-dPEG®24-amido-dPEG®23-amine

>95% (HPLC)

Synonym(s):
t-Boc-PEG-amine, t-Boc-N-amido-PEG24-amido-PEG23-amine, t-Boc-PEG47-NH2
Empirical Formula (Hill Notation):
C104H209N3O50
Molecular Weight:
2301.76

assay

>95% (HPLC)

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations

polymer architecture

shape: linear
functionality: homobifunctional

shipped in

ambient

storage temp.

−20°C

Inchi Code

1S/C104H209N3O50/c1-104(2,3)157-103(109)107-7-11-113-15-19-117-23-27-121-31-35-125-39-43-129-47-51-133-55-59-137-63-67-141-71-75-145-79-83-149-87-91-153-95-99-156-101-100-154-96-92-150-88-84-146-80-76-142-72-68-138-64-60-134-56-52-130-48-44-126-40-36-122-32-28-118-24-20-114-16-12-110-8-4-102(108)106-6-10-112-14-18-116-22-26-120-30-34-124-38-42-128-46-50-132-54-58-136-62-66-140-70-74-144-78-82-148-86-90-152-94-98-155-97-93-151-89-85-147-81-77-143-73-69-139-65-61-135-57-53-131-49-45-127-41-37-123-33-29-119-25-21-115-17-13-111-9-5-105/h4-101,105H2,1-3H3,(H,106,108)(H,107,109)

InChI key

UXZRMNJKCOFALH-UHFFFAOYSA-N

Features and Benefits

t-Boc-dPEG24-amido-dPEG23-amine is an increasingly popular choice for homobifunctional crosslinking. A tert-butyl group protects one end of this diamine-functionalized monodispersed PEG crosslinker. Carboxylic acids, aldehydes, and ketones react with both ends of the crosslinker. Carboxylic acids form amide bonds, while aldehydes and ketones react to form Schiff bases that are reducible to secondary amines. The mono-protected end of the molecule gives the user tighter control over crosslinking. The single molecular weight, discrete chain-length PEG linker is 149 atoms (107.7 Å) long and is the monodisperse PEG equivalent to PEG2000.

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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