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Key Documents

S5130

Sigma-Aldrich

Silica, fumed

powder

Synonym(s):

Silica, Silicic anhydride, Silicon dioxide, Silicon dioxide amorphous

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About This Item

Linear Formula:
SiO2
CAS Number:
Molecular Weight:
60.08
MDL number:
UNSPSC Code:
12352300
PubChem Substance ID:
NACRES:
NA.23

form

powder

surface area

395 m2/g (±25 m2/g)

refractive index

n20/D 1.46 (lit.)

density

2.3 lb/cu.ft at 25 °C (bulk density)(lit.)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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General description

Fumed silica may be synthesized by high temperature hydrolysis of SiCl4 in O2(N2)/H2 flame. It is amorphous in nature and possesses very high specific area. The micro droplets of amorphous silica fuse into a branch and form a chain like agglomerate.

Application

Fumed silica is used to deplete lipids and hormones in Taqman assays of human hepatoma cells HuH-7 and human liver cell line HepG2. Preparation of epoxidized natural rubber/fumed silica composites have been reported. Interaction of Gemini surfactant C12-s-C122Br with aqueous suspension of fumed silica has been studied. Fumed silica based nanocomposites reinforced with organo clay may be prepared. TiO2/fumed silica porous ceramic material was used to prepare photocatalytic materials.

Features and Benefits

Has interesting thickening and thixotropic properties, and an enormous external surface area.

Other Notes

Particle sizes are for primary particles, which form branched, chain-like aggregates a few tenths of a micron long.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Melt rheology of organoclay and fumed silica nanocomposites
Ph. Cassagnau
Polymer, 49(9), 2183-2196 (2008)
Preparation and properties of TiO2/fumed silica composite photocatalytic materials
Yu Y, et al.
Procedia Engineering, 27, 448-456 (2012)
Petra Thulin et al.
International journal of molecular medicine, 21(6), 819-824 (2008-05-29)
The peroxisome proliferator-activated receptor delta (PPARdelta) is a transcription factor that regulates genes of importance in lipid and glucose metabolism. ApoA-II is one of the major proteins of the HDL-particle. The aim of this study was to investigate the regulation
Interaction Between Fumed-Silica and Epoxidized Natural Rubber
Luo YY, et al.
Journal of Inorganic and Organometallic Polymers and Materials, 21(4), 777-783 (2011)
Ivan S Pires et al.
Biotechnology progress, 36(5), e3010-e3010 (2020-04-30)
Haptoglobin (Hp) is a plasma glycoprotein that scavenges cell-free hemoglobin (Hb). Hp has various potential therapeutic applications, but it has been mainly studied for treatment of acute hemolytic conditions that can arise from situations such as massive blood transfusion, infusion

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