Silica, fumed


Silica, Silicon dioxide, Silicic anhydride, Silicon dioxide amorphous
Linear Formula:
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:



Quality Level

refractive index

n20/D 1.46 (lit.)

surface area

395 m2/g±25 m2/g


2.3 lb/cu.ft at 25 °C (bulk density)(lit.)

SMILES string




InChI key


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General description

Fumed silica may be synthesized by high temperature hydrolysis of SiCl4 in O2(N2)/H2 flame. It is amorphous in nature and possesses very high specific area. The micro droplets of amorphous silica fuse into a branch and form a chain like agglomerate.


Fumed silica is used to deplete lipids and hormones in Taqman assays of human hepatoma cells HuH-7 and human liver cell line HepG2. Preparation of epoxidized natural rubber/fumed silica composites have been reported. Interaction of Gemini surfactant C12-s-C122Br with aqueous suspension of fumed silica has been studied. Fumed silica based nanocomposites reinforced with organo clay may be prepared. TiO2/fumed silica porous ceramic material was used to prepare photocatalytic materials.


25, 100 g in poly bottle
500 g in poly drum

Features and Benefits

Has interesting thickening and thixotropic properties, and an enormous external surface area.

Other Notes

Particle sizes are for primary particles, which form branched, chain-like aggregates a few tenths of a micron long.


13 - Non Combustible Solids

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Interaction Between Fumed-Silica and Epoxidized Natural Rubber
Luo YY, et al.
Journal of Inorganic and Organometallic Polymers and Materials, 21(4), 777-783 (2011)
Zheng O, et al.
Energy Procedia, 16 Part B, 1211-1219 (2012)
Tangential flow filtration of haptoglobin.
Pires, et al.
Biotechnology Progress, 36, e3010-e3010 (2020)
Petra Thulin et al.
International journal of molecular medicine, 21(6), 819-824 (2008-05-29)
The peroxisome proliferator-activated receptor delta (PPARdelta) is a transcription factor that regulates genes of importance in lipid and glucose metabolism. ApoA-II is one of the major proteins of the HDL-particle. The aim of this study was to investigate the regulation...
Melt rheology of organoclay and fumed silica nanocomposites
Ph. Cassagnau
Polymer, 49(9), 2183-2196 (2008)

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