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T27502

Sigma-Aldrich

L-4-Thiazolidinecarboxylic acid

98%

Synonym(s):

L-Thiaproline

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$91.10
100 G
$625.00

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10 G
$91.10
100 G
$625.00

About This Item

Empirical Formula (Hill Notation):
C4H7NO2S
CAS Number:
34592-47-7
Molecular Weight:
133.17
Beilstein/REAXYS Number:
81065
EC Number:
252-106-3
MDL number:
MFCD00005212
UNSPSC Code:
12352106
PubChem Substance ID:
24900069
NACRES:
NA.22

$91.10

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Quality Level

200

assay

98%

form

powder

optical activity

[α]20/D −141°, c = 1.3 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

color

white

mp

190-200 °C (dec.) (lit.)

SMILES string

OC(=O)[C@@H]1CSCN1

InChI

1S/C4H7NO2S/c6-4(7)3-1-8-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1

InChI key

DZLNHFMRPBPULJ-VKHMYHEASA-N

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Related Categories

Application

Used in peptide coupling reactions.[1]

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV6048
MKCR4193
MKCL3512
MKCG1270
MKBW6578V

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Bioorganic & Medicinal Chemistry Letters, 4, 887-887 (1994)
Masashi Suo et al.
Cancer letters, 237(2), 256-262 (2005-07-30)
An excessive duodenal reflux induced by surgery has been widely accepted to cause gastric carcinogenesis in the remnant stomach. As one of causative factors for malignancy, N-nitroso compounds produced by enteric bacteria have been postulated. However, there is no concrete
Pedro P Corbi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71(3), 929-931 (2008-03-21)
A new water-soluble lithium salt of thiazolidine-4-carboxylic acid was synthesized and characterized by chemical and spectroscopic techniques. Elemental and mass spectrometric (ESI-MS) analyses of the solid compound fit to the composition LiC(4)H(6)NSO(2). (1)H, (13)C nuclear magnetic resonance (NMR), [(1)H-(15)N] NMR
Florine Cavelier et al.
Journal of peptide science : an official publication of the European Peptide Society, 12(10), 621-625 (2006-06-21)
As proline plays an important role in biologically active peptides, many analogues of this residue have been developed to modulate the proportion of cis and trans conformers. A correlation between the pyrrolidine ring shape and structural properties of proline has
Ana Navarro et al.
Antioxidants & redox signaling, 9(1), 131-141 (2006-11-23)
Male mice on a diet supplemented with thioproline (l-thiazolidine-4-carboxylic acid), a physiological metabolite of 5-hydroxytryptamine, at 2.0 g/kg of food from 28 weeks of age and for their entire life, showed a 23-29% increased median and maximal life span. These
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