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W222455

Sigma-Aldrich

Caffeine

anhydrous, natural, 99%, FCC, FG

Synonym(s):
1,3,7-Trimethylxanthine
Empirical Formula (Hill Notation):
C8H10N4O2
CAS Number:
Molecular Weight:
194.19
FEMA Number:
2224
Beilstein:
17705
MDL number:
Flavis number:
16.016

grade

FG
Halal
Kosher
anhydrous
natural

Quality Level

reg. compliance

EU Regulation 1333/2008 & 178/2002
FCC
FDA 21 CFR 117

Assay

99%

mp

234-236.5 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

Organoleptic

odorless

SMILES string

CN1C(=O)N(C)c2ncn(C)c2C1=O

InChI

1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

InChI key

RYYVLZVUVIJVGH-UHFFFAOYSA-N

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This Item
W222402C17781.02584
Caffeine anhydrous, natural, 99%, FCC, FG

Sigma-Aldrich

W222455

Caffeine

Caffeine anhydrous, 99%, FCC, FG

Sigma-Aldrich

W222402

Caffeine

Caffeine Sigma Reference Standard, vial of 250 mg

Sigma-Aldrich

C1778

Caffeine

Caffeine EMPROVE® ESSENTIAL Ph Eur,BP,USP

SAFC

1.02584

Caffeine

assay

99%

assay

99%

assay

-

assay

98.5-101.0% (HPLC), 98.5-101.0% (perchloric acid titration)

mp

234-236.5 °C (lit.)

mp

234-236.5 °C (lit.)

mp

234-236.5 °C (lit.)

mp

235-239 °C

documentation

see Safety & Documentation for available documents

documentation

see Safety & Documentation for available documents

documentation

-

documentation

-

food allergen

no known allergens

food allergen

no known allergens

food allergen

-

food allergen

-

organoleptic

odorless

organoleptic

odorless

organoleptic

-

organoleptic

-

Biochem/physiol Actions

A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


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