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W225207

β-Caryophyllene

≥80%, FCC, FG

Synonym(s):

(−)-trans-Caryophyllene, trans-(1R,9S)-8-Methylene-4,11,11-trimethylbicyclo[7.2.0]undec-4-ene

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1 each

Available to ship TODAYfromSHEBOYGAN FALLS

$58.00
1 kg

Available to ship TODAYfromSHEBOYGAN FALLS

$84.80
9 kg

Available to ship TODAYfromSHEBOYGAN FALLS

$490.00
20 kg

Available to ship TODAYfromMILWAUKEE

$595.00
$446.25

About This Item

Empirical Formula (Hill Notation):
C15H24
CAS Number:
Molecular Weight:
204.35
FEMA Number:
2252
Council of Europe no.:
2618
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
1.007
EC Number:
201-746-1
NACRES:
NA.21
MDL number:
Beilstein/REAXYS Number:
2044564
Organoleptic:
spicy; woody
Grade:
FG, Fragrance grade, Halal, Kosher
Biological source:
synthetic
Agency:
follows IFRA guidelines, meets purity specifications of JECFA
Food allergen:
no known allergens

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biological source

synthetic

Quality Segment

grade

FG, Fragrance grade, Halal, Kosher

agency

follows IFRA guidelines, meets purity specifications of JECFA

reg. compliance

EU Regulation 1223/2009, EU Regulation 1334/2008 & 178/2002, FCC, FDA 21 CFR 117, FDA 21 CFR 172.515

assay

≥80%

optical activity

[α]23/D −7.5°, neat

composition

contains β-Caryophyllene

refractive index

n20/D 1.5 (lit.)

bp

129-130 °C/14 mmHg (lit.)

density

0.901 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

β-caryophyllene (ox.)

organoleptic

spicy; woody

SMILES string

C\C1=C/CCC(=C)[C@H]2CC(C)(C)[C@@H]2CC1

InChI

1S/C15H24/c1-11-6-5-7-12(2)13-10-15(3,4)14(13)9-8-11/h6,13-14H,2,5,7-10H2,1,3-4H3/b11-6+/t13-,14-/m1/s1

InChI key

NPNUFJAVOOONJE-GFUGXAQUSA-N

General description

β;-Caryophyllene is a volatile sesquiterpene compound that can be used as a flavoring agent. It is one of the major volatile organic compounds in Eugenia caryophyllata essential oil, Psidium guajava L. leaves, Arabidopsis thaliana flowers and Artemisia annua L. aerial parts.

Application


  • Essential Oil Constituents as Anti-Inflammatory and Neuroprotective Agents: An Insight through Microglia Modulation.: β-Caryophyllene shows significant potential as an anti-inflammatory and neuroprotective agent by modulating microglia, which plays a crucial role in neuroinflammation (Stojanovic et al., 2024) (Stojanovic et al., 2024).

  • Synergistic Antinociceptive Effect of β-Caryophyllene Oxide in Combination with Paracetamol, and the Corresponding Gastroprotective Activity.: This research demonstrates that β-caryophyllene oxide, when combined with paracetamol, has enhanced antinociceptive effects and provides gastroprotection (Espinosa-Juárez et al., 2024) (Espinosa-Juárez et al., 2024).

  • Consumption of β-Caryophyllene Increases the Mating Success of Bactrocera zonata Males (Diptera: Tephritidae).: The study explores how β-caryophyllene consumption boosts the mating success of male fruit flies, indicating its potential applications in pest control strategies (Ul Haq et al., 2024) (Ul Haq et al., 2024).

  • Development of ophthalmic nanoemulsions of β-caryophyllene for the treatment of Acanthamoeba keratitis.: This research focuses on creating nanoemulsions containing β-caryophyllene for treating Acanthamoeba keratitis, demonstrating its potential in ophthalmic therapies (Santos Porto et al., 2024) (Santos Porto et al., 2024).


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This Item
W225299PHL8071775541
description

≥80%, FCC, FG

description

natural, ≥80%, FG

description

phyproof® Reference Substance

description

analytical standard

organoleptic

spicy; woody

organoleptic

woody; spicy

organoleptic

-

organoleptic

-

grade

Kosher, FG, Fragrance grade, Halal

grade

FG, Halal, natural, Kosher, Fragrance grade

grade

primary reference standard

grade

analytical standard

biological source

synthetic

biological source

botanical

biological source

-

biological source

-

food allergen

no known allergens

food allergen

no known allergens

food allergen

-

food allergen

-

documentation

see Safety & Documentation for available documents

documentation

see Safety & Documentation for available documents

documentation

-

documentation

-

assay

≥80%

assay

≥80%

assay

≥95.0% (GC)

assay

≥98.0% (sum of enantiomers, GC)


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pictograms

Health hazardExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Asp. Tox. 1 - Skin Sens. 1B

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

221.9 °F - closed cup

flash_point_c

105.5 °C - closed cup

ppe

Eyeshields, Gloves



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Questions

1–4 of 4 Questions  
  1. May I ask the storage temperate and condition when aliquot the beta-Caryophyllene into centrifuge tube

    1 answer
    1. The product is chemically stable under standard ambient conditions (room temperature) .

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  4. Respected Sir, You have mentioned the sample-K in the product description, and i need to know what sample-k and what it contains, either beta caryophyllene mixed in any solution or not?

    1 answer
    1. This product, W225207-SAMPLE-K, is a pack size of 10 mg. Beta-caryophyllene is a pure liquid and is not mixed in any solution, with a purity of approximately 93.1%, depending on the lot number.

      Helpful?

Reviews

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  1. Piacenza
    • Review 1
    • Vote 1
    5 out of 5 stars.

    Servizio eccellente, prodotto conforme alle aspettative. Consigliato

    Servizio eccellente, prodotto conforme alle aspettative. Consigliato

    Helpful?