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W228818

Sigma-Aldrich

trans-Cinnamic acid

≥99%, FG

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Synonym(s):
trans-3-Phenylacrylic acid, Cinnamic acid
Linear Formula:
C6H5CH=CHCOOH
CAS Number:
Molecular Weight:
148.16
FEMA Number:
2288
Beilstein/REAXYS Number:
1905952
EC Number:
Council of Europe no.:
22
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
8.022
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

FG
Fragrance grade
Halal
Kosher

agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117

assay

≥99%

bp

300 °C (lit.)

mp

132-135 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

organoleptic

cinnamon; honey; floral; spicy; sweet

SMILES string

OC(=O)\C=C\c1ccccc1

InChI

1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+

InChI key

WBYWAXJHAXSJNI-VOTSOKGWSA-N

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Related Categories

Application


  • Therapeutic Implications of Phenolic Acids for Ameliorating Inflammatory Bowel Disease.: This review highlights the therapeutic potential of phenolic acids, including trans-cinnamic acid, in treating inflammatory bowel disease (IBD). The anti-inflammatory properties of trans-cinnamic acid are discussed, showcasing its promise as a natural treatment option for IBD (Lu and Han, 2024).

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

wgk_germany

WGK 1

flash_point_f

320.0 °F

flash_point_c

160 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

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Pentameric ligand gated ion channels (pLGICs) mediate signal transduction. The binding of an extracellular ligand is coupled to the transmembrane channel opening. So far, all known agonists bind at the interface between subunits in a topologically conserved "orthosteric site" whose
Ying Lei et al.
International journal of pharmaceutics, 453(2), 579-586 (2013-06-13)
Herein, we reported a new type of self-assembly micelles based on amphiphilic polymers of cinnamate and coumarin derivatives modified PEG for drug delivery applications. Lipophilic cinnamic acid (CIN) and 7-carboxyl methoxycoumarin (COU) were immobilized on the terminal groups of poly(ethylene
Qian Fan et al.
Food chemistry, 134(2), 1081-1087 (2012-10-31)
Nine cinnamoyl amides with amino acid ester (CAAE) moiety were synthesized by the conjugation of the corresponding cinnamic acids (cinnamic acid, 4-hydroxy cinnamic acid, ferulic acid and caffeic acid) with amino acid esters, and their inhibitory effects on the activities
Stanislava Gorjanović et al.
Journal of agricultural and food chemistry, 60(38), 9573-9580 (2012-09-07)
Hydrogen peroxide scavenging (HPS) activity of unfermented (green, yellow, and white), partially fermented (oolong), and completely fermented (black) tea ( Camellia sinensis ), maté ( Ilex paraguariensis ), and various herbal infusions, as well as individual compounds (flavan-3-ols, flavonols, cinnamic

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