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W271004

Sigma-Aldrich

Methyl 4-hydroxybenzoate

≥99%, FCC

Synonym(s):
NIPAGIN, p-Hydroxybenzoic acid methyl ester, Methyl paraben
Linear Formula:
HOC6H4CO2CH3
CAS Number:
Molecular Weight:
152.15
FEMA Number:
2710
Beilstein:
509801
EC Number:
Council of Europe no.:
657c
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

biological source

synthetic

grade

Kosher

Agency/Method

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
EU Regulation 178/2002
FCC
FDA 21 CFR 172.515

assay

≥99%

mp

125-128 °C (lit.)

Documentation

see Safety & Documentation for available documents

Featured Industry

Flavors and Fragrances

Organoleptic

odorless

food allergen

no known allergens

fragrance allergen

no known allergens

SMILES string

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

Gene Information

rat ... Ar(24208)

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Related Categories

General description

Methyl 4-hydroxybenzoate is commonly used as an antimicrobial preservative in foods, drugs and cosmetics. It occurs naturally in Securidaca longepedunculata Fers roots.

Packaging

5, 10 kg in fiber drum
1 kg in poly bottle

Pictograms

Environment

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 1

Flash Point(F)

334.4 °F

Flash Point(C)

168 °C

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Evaluation of the health aspects of methyl paraben: a review of the published literature.
Soni MG, et al.
Food And Chemical Toxicology, 40(10, 1335-1373 (2002)
Essential oils of Nigeria II: analysis of the leaf oil of Securidaca longependuculata Fers.
Adebayo MA, et al.
J. Essent. Oil Res., 19(5, 452-454 (2007)
Raena Morley et al.
Journal of chromatography. A, 1501, 26-38 (2017-05-05)
Trapping multiple dual mode centrifugal partition chromatography (trapping MDM CPC) is an alternative to isocratic pulse injections for the separation of intermediately-eluting components from complex mixtures using liquid-liquid chromatography. In this work, a throughput maximization strategy is developed and validated...
Jia Chen et al.
Journal of chromatography. A, 1591, 33-43 (2019-01-21)
A novel supramolecular solvent (SUPRAS) based on hexafluoroisopropanol (HFIP)/Brij-35 was proposed for liquid-phase microextraction (LPME) of parabens in water samples, pharmaceuticals and personal care products. Brij-35 is a cost-effective and non-toxic non-ionic surfactant, but it has a high cloud point...
Kate Hoffman et al.
Environment international, 119, 26-36 (2018-06-22)
Semi-volatile organic compounds (SVOCs) are used extensively in consumer and personal care products; electronics; furniture; and building materials and are detected in most indoor environments. As a result, human exposure to mixtures of SVOCs is wide-spread. However, very few studies...

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