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W296309

Sigma-Aldrich

(R)-(+)-Pulegone

≥90%

Synonym(s):
(+)-Pulegone, (R)-2-Isopropylidene-5-methylcyclohexanone, (R)-p-Menth-4(8)-en-3-one, p-Menth-4(8)-en-3-one
Empirical Formula (Hill Notation):
C10H16O
CAS Number:
Molecular Weight:
152.23
FEMA Number:
2963
Beilstein:
2040703
EC Number:
Council of Europe no.:
2050c
MDL number:
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

Kosher

vapor pressure

138 mmHg ( 25 °C)

Assay

≥90%

optical activity

[α]20/D +22°, neat

refractive index

n20/D 1.486 (lit.)

bp

224 °C (lit.)

density

0.937 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

Organoleptic

herbaceous; minty; sulfurous; sweet

SMILES string

C[C@@H]1CC\C(=C(\C)C)C(=O)C1

InChI

1S/C10H16O/c1-7(2)9-5-4-8(3)6-10(9)11/h8H,4-6H2,1-3H3/t8-/m1/s1

InChI key

NZGWDASTMWDZIW-MRVPVSSYSA-N

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1 of 4

This Item
PHL82240376388P55708
(R)-(+)-Pulegone ≥90%

Sigma-Aldrich

W296309

(R)-(+)-Pulegone

(+)-Pulegone phyproof® Reference Substance

PHL82240

(+)-Pulegone

(R)-(+)-Pulegone ≥90%

Sigma-Aldrich

376388

(R)-(+)-Pulegone

(R)-(+)-Pulegone 85%, technical grade

Sigma-Aldrich

P55708

(R)-(+)-Pulegone

grade

Kosher

grade

primary reference standard

grade

-

grade

technical grade

assay

≥90%

assay

≥95.0% (GC)

assay

≥90%

assay

85%

optical activity

[α]20/D +22°, neat

optical activity

-

optical activity

[α]20/D +23.5°, neat

optical activity

[α]20/D +22°, neat

refractive index

n20/D 1.486 (lit.)

refractive index

-

refractive index

n20/D 1.486 (lit.)

refractive index

n20/D 1.486 (lit.)

bp

224 °C (lit.)

bp

223-224 °C (lit.)

bp

224 °C (lit.)

bp

224 °C (lit.)

Biochem/physiol Actions

Taste at 20 ppm

Other Notes

Natural occurrence: Buchu oil, native spearmint, pennyroyal, peppermint, scotch spearmint and thyme.

Pictograms

Exclamation markHealth hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

179.6 °F - closed cup

Flash Point(C)

82 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Chang-Qin Li et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(21), 3173-3175 (2013-02-13)
To study the validity of Schizonepeta tenuifalia pieces. The change principle for the contents of essential oil and pulegone was determined by the way of classical constant temperature acceleration experiment, and the reacting speed at 20 degrees C was calculated
Mitscheli S Da Rocha et al.
Toxicological sciences : an official journal of the Society of Toxicology, 128(1), 1-8 (2012-04-14)
Essential oils from mint plants, including peppermint and pennyroyal oils, are used at low levels as flavoring agents in various foods and beverages. Pulegone is a component of these oils. In a 2-year bioassay, oral administration of pulegone slightly increased
Mosciano, G.
Perfumer & Flavorist, 30, 56-56 (2005)
Feng Li et al.
Chemical research in toxicology, 24(5), 744-751 (2011-04-08)
A predominant pathway of xenobiotic-induced toxicity is initiated by bioactivation. Characterizing reactive intermediates will provide information on the structure of reactive species, thereby defining a potential bioactivation mechanism. Because most reactive metabolites are not stable, it is difficult to detect
Sung-Hwa Sohn et al.
Cellular immunology, 277(1-2), 58-65 (2012-06-26)
It has long been believed that mast cells play a crucial role in the development of many physiological changes during immediate allergic responses. This study was conducted to evaluate the anti-inflammation mechanism of Schizonepeta tenuifolia (ST) extract and ST purified

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