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W328502

Sigma-Aldrich

L-Glutamic acid

FCC

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Synonym(s):
(S)-2-Aminopentanedioic acid, Glu
Linear Formula:
HO2CCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
147.13
FEMA Number:
3285
Beilstein/REAXYS Number:
1723801
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.21

biological source

corn

Quality Level

grade

Kosher

reg. compliance

FCC
FDA 21 CFR 172.320
FDA 21 CFR 182.1045

assay

98.5-101.5% dry basis (perchloric acid titration)

form

powder or crystals

optical activity

[α]20/D +32°, c = 10 in 2 M HCl

mp

205 °C (dec.) (lit.)

solubility

water: soluble 8.64 g/L at 25 °C

density

1.54 g/cm3 at 20 °C

cation traces

As: ≤3 ppm
Cd: ≤1 ppm
Hg: ≤1 ppm
Pb: ≤5 ppm

application(s)

flavors and fragrances

food allergen

no known allergens

organoleptic

baked

SMILES string

N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

InChI key

WHUUTDBJXJRKMK-VKHMYHEASA-N

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This Item
95436PHR1107G8415
L-Glutamic acid FCC

W328502

L-Glutamic acid

L-Glutamic acid certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

95436

L-Glutamic acid

L-Glutamic acid Pharmaceutical Secondary Standard; Certified Reference Material

PHR1107

L-Glutamic acid

L-Glutamic acid from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%

G8415

L-Glutamic acid

organoleptic

baked

organoleptic

-

organoleptic

-

organoleptic

-

biological source

corn

biological source

-

biological source

-

biological source

non-animal source

food allergen

no known allergens

food allergen

-

food allergen

-

food allergen

-

assay

98.5-101.5% dry basis (perchloric acid titration)

assay

-

assay

-

assay

98.5-100.5%

density

1.54 g/cm3 at 20 °C

density

-

density

-

density

1.54 g/cm3 at 20 °C

General description

L-Glutamic acid is an amino acid mainly used as a flavor enhancer in the food industry. It occurs naturally in kelp. L-Glutamic acid is said to impart umami-like taste in ready-to-drink (RTD) green tea.

Biochem/physiol Actions

An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Glutamate is the principal excitatory neurotransmitter and is involved in normal brain function. Cognitive impairment is common in multiple sclerosis (MS), and understanding its mechanisms is crucial for developing effective treatments. We used structural and metabolic brain imaging to test

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