MilliporeSigma
All Photos(2)

W355690

Sigma-Aldrich

Isopropyl myristate

≥98%

Synonym(s):
Myristic acid isopropyl ester, IPM 100, IPM, IPM-R, Isopropyl tetradecanoate, IPM-EX
Linear Formula:
CH3(CH2)12COOCH(CH3)2
CAS Number:
Molecular Weight:
270.45
FEMA Number:
3556
Beilstein:
1781127
EC Number:
Council of Europe no.:
386
MDL number:
PubChem Substance ID:
Flavis number:
9.105
NACRES:
NA.21

Quality Level

biological source

synthetic

grade

Fragrance grade
Halal
Kosher

Agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009

assay

≥98%

refractive index

n20/D 1.434 (lit.)

bp

193 °C/20 mmHg (lit.)

mp

~3 °C (lit.)

density

0.85 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

Organoleptic

faint; fatty; oily

SMILES string

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

InChI key

AXISYYRBXTVTFY-UHFFFAOYSA-N

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General description

Isopropyl myristate is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. It is also used as a flavoring agent in the food industry.

Packaging

8, 20 kg in poly drum
1 kg in poly bottle

Biochem/physiol Actions

Odor at 1.0%
Taste at 10 ppm

Storage Class Code

10 - Combustible liquids

WGK

awg

Flash Point(F)

305.6 °F - closed cup

Flash Point(C)

152 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Handbook of Preservatives, 425-425 (2004)
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized
Fan Yang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(1), 158-163 (2012-06-21)
Transdermal delivery of methotrexate (MTX) was investigated by using the solid-in-oil (S/O) technique. Because MTX was coated with nonionic surfactant molecules, the resulting complex was easy to dissolve in various organic solvents and provided a transparent solution in isopropyl myristate
Rajbharan Yadav et al.
Antimicrobial agents and chemotherapy, 59(4), 2286-2298 (2015-02-04)
Acinetobacter baumannii is among the most dangerous pathogens and emergence of resistance is highly problematic. Our objective was to identify and rationally optimize β-lactam-plus-aminoglycoside combinations via novel mechanism-based modeling that synergistically kill and prevent resistance of carbapenem-resistant A. baumannii. We

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