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W527602

Sigma-Aldrich

L-Isoleucine

99%, FCC, FG

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Synonym(s):
(2S,3S)-2-Amino-3-methylpentanoic acid
Linear Formula:
C2H5CH(CH3)CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
Beilstein/REAXYS Number:
1721792
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

FG

reg. compliance

EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 172.320

assay

99%

form

crystalline powder

optical activity

[α]20/D +38.6 to +42.5°, c = 4 in 6 M HCl

mp

288 °C (dec.) (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

odorless

SMILES string

CC[C@H](C)[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1

InChI key

AGPKZVBTJJNPAG-WHFBIAKZSA-N

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1 of 4

This Item
PHR1099I275256241
vibrant-m

W527602

L-Isoleucine

-
vibrant-m

PHR1099

L-Isoleucine

-
vibrant-m

I2752

L-Isoleucine

Essential Grade
vibrant-m

56241

L-Isoleucine

-
food allergen

no known allergens

food allergen

-

food allergen

-

food allergen

-

grade

FG

grade

certified reference material, pharmaceutical secondary standard

grade

reagent grade

grade

certified reference material, TraceCERT®

biological source

synthetic

biological source

-

biological source

-

biological source

-

optical activity

[α]20/D +38.6 to +42.5°, c = 4 in 6 M HCl

optical activity

-

optical activity

-

optical activity

-

mp

288 °C (dec.) (lit.)

mp

288 °C (dec.) (lit.)

mp

288 °C (dec.) (lit.)

mp

288 °C (dec.) (lit.)

General description

L-Isoleucine is an essential amino acid used as a supplement in sports nutrition. It is one of the free-amino acids found in common buckwheat.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Zorn H and Czermak P
Biotechnology of Food and Feed Additives., 219-220 null
Flavor components in buckwheat bread
Lin LY, et al
Journal of Food Processing and Preservation, 33(6), 814-826 (2009)
Urho M Kujala et al.
Circulation, 127(3), 340-348 (2012-12-22)
Long-term physical inactivity seems to cause many health problems. We studied whether persistent physical activity compared with inactivity has a global effect on serum metabolome toward reduced cardiometabolic disease risk. Sixteen same-sex twin pairs (mean age, 60 years) were selected
Eva Blomstrand et al.
The Journal of nutrition, 136(1 Suppl), 269S-273S (2005-12-21)
BCAAs (leucine, isoleucine, and valine), particularly leucine, have anabolic effects on protein metabolism by increasing the rate of protein synthesis and decreasing the rate of protein degradation in resting human muscle. Also, during recovery from endurance exercise, BCAAs were found
L Edvinsson
Blood vessels, 28(1-3), 35-45 (1991-01-01)
The cerebral circulation is supplied with two vasodilator systems: the parasympathetic system storing vasoactive intestinal peptide, peptide histidine isoleucine, acetylcholine and in a subpopulation of nerves neuropeptide Y, and the sensory system, mainly originating in the trigeminal ganglion, storing substance

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