100403X

GPC-d9

Avanti Research^™ - A Croda Brand

• Synonym(s): (d9)choline alfoscerate; α-GPC(d9); α-GPC(d9)
• Empirical Formula (Hill Notation): C₈H₁₁D₉NO₆P
• CAS Number: 2260669-07-4
• Molecular Weight: 266.28
• MDL number: MFCD00152125
• NACRES: NA.25
• UNSPSC Code: 51321705
• Assay: >99% phosphorus (P) basis (qNMR)
• Form: solution

Properties

• description: L-α-glycerophosphoryl(choline-d9), water:ethanol (9:1)
• assay: >99% phosphorus (P) basis (qNMR)
• form: solution
• packaging: pkg of 1 × 1 mL (100403X-100ug)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• concentration: 0.1 mg/mL (100403X-100ug)
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

GPC rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter.

Glycerophosphocholine (GPC), is a water-soluble deacylated phosphatidylcholine derivative.[1] It is majorly generated from choline based phospholipids associated with membranes. GPC is widely distributed in human blood and saliva.[2] L-α-glycerophosphoryl(choline-d9) (GPC-d9) is the deuterium-labeled form of GPC.[3]

Application

GPC-d9 has been used as an internal standard in ultra-performance liquid chromatograph coupled to a SCIEX 4500QT mass spectrometer (UPLC-MS/MS) for the quantification of choline compounds from whole milk samples.[4]

Biochem/physiol Actions

Glycerophosphocholine (GPC) protects mitochondrial respiratory complex I during oxidative stress associated with liver ischemia-reperfusion.[1] GPC is an ergogenic supplement that improves muscle force production.[5] The deuterium-labeled glycerophosphocholine is employed as an internal standard for human milk choline quantification using liquid chromatography-tandem mass spectrometry.[3]

Packaging

5 mL Clear Glass Sealed Ampule (100403X-100ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable