MilliporeSigma
All Photos(1)

699854P

Avanti

4A-MPLA (isomer C3)

Avanti Polar Lipids 699854P, powder

Synonym(s):
Monophosphopdyl Tetra-acyl Lipid A
Empirical Formula (Hill Notation):
C68H132N3O19P
Molecular Weight:
1326.76
NACRES:
NA.25

assay

>99% (HPLC)

form

powder

packaging

pkg of 1 × 1 mg (699854P-1mg)
pkg of 1 × 5 mg (699854P-5mg)

manufacturer/tradename

Avanti Polar Lipids 699854P

application(s)

vaccine development

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@H]([C@@H](CO[C@@H]([C@@H]1NC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCCCCCCC)=O)O[C@H](CO)[C@@H](OP([O-])(O)=O)[C@@H]1O)O[C@H](O)[C@@H]2NC(C[C@H](O)CCCCCCCCCCC)=O)[C@@H]2OC(C[C@H](O)CCCCCCCCCCC)=O.[NH4+]

Biochem/physiol Actions

Structural modification of diphosphoryl lipid A by hydrolysis produces MPLA (monophosphoryl lipid A) and is known to decrease its toxicity. MPLA, a lipopolysaccharide derivative, acts an immunomodulator and is non-toxic. For this reason, it is useful as a vaccine adjuvant. The MPLA induced immune response is tissue specific. It enhances host′s resistance against endotoxin induced effects. It also decreases cytokine production during infection.

Packaging

2 mL Amber Glass Crimp Cap Vial (699854P-1mg)
2 mL Amber Glass Crimp Cap Vial (699854P-5mg)

Other Notes

For R&D use only. Not for drug, household, or other uses.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

SDS

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service