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700037P

Avanti

24(R/S),25-epoxycholesterol

powder

Empirical Formula (Hill Notation):
C27H44O2
CAS Number:
Molecular Weight:
400.64
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (700037P-1mg)

manufacturer/tradename

Avanti Polar Lipids 700037P

shipped in

dry ice

storage temp.

−20°C

Application

24(R/S),25-epoxycholesterol has been used as liver X receptor ligand in breast cancer cell lines.

Biochem/physiol Actions

24(R/S),25-epoxycholesterol (24(R/S),25-EC) is a side chain substituted cholesterol. It is an effective activator of liver X receptor (LXR) transcription. 24R and 24S epimers of epoxycholesterol inhibit cholesterol synthesis from 24,25-dihydrolanosterol. The levels of 24(R/S),25-EC is elevated in gastric carcinoma and may also inhibit gastric tumor invasion. 24(R/S),25-EC regulates gastric epithelial function and also may modulates the phosphatidylinositol 3-kinase - protein kinase B (PI3K/AKT) signaling.

Packaging

5 mL Amber Glass Screw Cap Vial (700037P-1mg)

Storage Class Code

13 - Non Combustible Solids

Certificate of Analysis

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Certificate of Origin

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Quotes and Ordering

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