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700094P

Avanti

cholestanol-d5

2,2,3,4,4-pentadeuterio-5α-cholestan-3β-ol, powder

Synonym(s):
111020
Empirical Formula (Hill Notation):
C27H43D5O
CAS Number:
Molecular Weight:
393.70
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700094P-1mg)

manufacturer/tradename

Avanti Polar Lipids 700094P

shipped in

dry ice

storage temp.

−20°C

General description

Cholestanol-d5 is a deuterated form of cholestanol. Cholestanol is a plant saturated sterol and has Δ5 double bond to the 5α position in the cholesterol structure and is a 5α-dihydro derivative of cholesterol.

Biochem/physiol Actions

Cholestanol deuterated has been administered in small intestine samples for the quantification of sterols by gas chromatography-mass spectrometry. The levels of cholesterol and cholestanol are elevated in tendons and brain in cerebrotendinous xanthomatosis due to the CYP27A1 (Cytochrome P450 Family 27 Subfamily A Member 1) deficiency. Cholestanol-d5 is useful as an internal standard to spike sediment samples for tandem mass spectrometry (MS/MS) for fecal sterol quantification. Cholestanol is a cholesterol absorption biomarker.

Packaging

5 mL Amber Glass Screw Cap Vial (700094P-1mg)

Storage Class Code

13 - Non Combustible Solids

Certificate of Analysis

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Certificate of Origin

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