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700119P

Avanti

7α,24(R/S)-dihydroxycholesterol-d7

7α,24(R/S)-dihydroxycholesterol-d7, powder

Synonym(s):
111113
Empirical Formula (Hill Notation):
C27H39D7O3
CAS Number:
Molecular Weight:
425.70
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700119P-1mg)

manufacturer/tradename

Avanti Polar Lipids 700119P

shipped in

dry ice

storage temp.

−20°C

General description

7α,24(R/S)-dihydroxycholesterol-d7 is a deuterated derivative of 7α,24(R/S)-dihydroxycholesterol and is a oxysterol.

Biochem/physiol Actions

7α,24(R/S)-dihydroxycholesterol is a racemic mixture. 7α,24(S)-dihydroxycholesterol (7α,24(S)-diOHC) is synthesized from 24(S)-OHC in the presence of enzyme oxysterol 7-α-hydroxylase 2 (CYP39A1). 7α,24(S)-diOHC is a ligand for liver X receptor (LXR).

Packaging

5 mL Amber Glass Screw Cap Vial (700119P-1mg)

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Obesity is associated with changes in oxysterol metabolism and levels in mice liver, hypothalamus, adipose tissue and plasma
Guillemot-Legris O, et al.
Scientific Reports null
Simple, stereocontrolled syntheses of 24 (S), 25-epoxy-22 (R)-hydroxycholesterol, 22 (R), 24 (S)-dihydroxycholesterol and diastereomers, new ligands for binding and activation of LXRs
Corey EJ and Grogan MJ
Tetrahedron Letters null

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