MilliporeSigma
All Photos(1)

700137P

Avanti

7β,27-dihydroxycholesterol-d6

Avanti Polar Lipids 700137P, powder

Synonym(s):
7β,27-dihydroxycholesterol-d6
Empirical Formula (Hill Notation):
C27H40D6O3
CAS Number:
Molecular Weight:
424.69
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700137P-1mg)

manufacturer/tradename

Avanti Polar Lipids 700137P

shipped in

dry ice

storage temp.

−20°C

General description

7β,27-dihydroxycholesterol-d6 is a deuterated derivative of 7β,27-dihydroxycholesterol. 7β,27-dihydroxycholesterol is a substrate for enzyme 11β-hydroxysteroid dehydrogenases (11β-HSDs).

Application

7β,27-dihydroxycholesterol-d6 has been used as an internal standard in ultra-performance liquid chromatography - tandem mass spectrometer (UPLC-MS/MS).

Biochem/physiol Actions

7β,27-dihydroxycholesterol (7β27OHC) serves as a ligand for retinoid-related orphan receptor γ (RORγ). 7β27OHC is also involved in smoothened (Smo) functionality.

Packaging

5 mL Amber Glass Screw Cap Vial (700137P-1mg)

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Katharina R Beck et al.
Journal of lipid research, 60(9), 1535-1546 (2019-07-06)
Oxysterols previously were considered intermediates of bile acid and steroid hormone biosynthetic pathways. However, recent research has emphasized the roles of oxysterols in essential physiologic processes and in various diseases. Despite these discoveries, the metabolic pathways leading to the different

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service