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700144P

Avanti

15:0 cholesteryl-d7 ester

Avanti Polar Lipids 700144P, powder

Synonym(s):
cholesteryl-d7 pentadecanoate
Empirical Formula (Hill Notation):
C42H67D7O2
CAS Number:
Molecular Weight:
618.08
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (700144P-10mg)
pkg of 1 × 25 mg (700144P-25mg)

manufacturer/tradename

Avanti Polar Lipids 700144P

shipped in

dry ice

storage temp.

−20°C

General description

15:0 cholesteryl-d7 ester (cholesteryl-d7 pentadecanoate) is a deuterated form of cholesteryl pentadecanoate ester. Cholesterol is found in free and ester form in circulation. It associates with lipoproteins including very-low, low and high-density lipoproteins (VLDL, LDL and HDL). The synthesis of cholesteryl esters is mediated by acylCoA-cholesteryl-acyl transferase (ACAT) majorly in the endoplasmic reticulum of liver and intestinal cells.

Biochem/physiol Actions

A ratio of cholesteryl ester to cholesterol is lower in cardiovascular disorder. The esterified cholesterol serves as the storage version of cholesterol and its association with lipoproteins further adds a structural feature to them.

Packaging

5 mL Amber Glass Screw Cap Vial (700144P-25mg)
5 mL Amber Glass Screw Cap Vial (700144P-10mg)

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Certificate of Analysis

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Certificate of Origin

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Mathias J Gerl et al.
Scientific reports, 8(1), 14764-14764 (2018-10-05)
Shotgun lipidomic analysis of 203 lipids in 13 lipid classes performed on blood plasma of donors who had just suffered an acute coronary syndrome (ACS, n = 74), or an ischemic stroke (IS, n = 21), or who suffer from stable angina pectoris (SAP
Babak Bagheri et al.
Medical archives (Sarajevo, Bosnia and Herzegovina), 72(2), 103-107 (2018-05-08)
The hypothesis is proposed that the atherogenicity of lipoporotein fractions is correlated with the content of unesterified cholesterol. To evaluate the role and prognostic values of unesterified and esterified cholesterol in lipoprotein fractions for coronary artery disease (CAD). The study

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