This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH® LIPIDOMIX® Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.
18:1-d7 Lyso PC 1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphocholine is a deuterated phospholipid. The lipid lysophosphatidylcholine is esterified with oleic acid. Oleic acid harbors the deuterium ions. Lysophosphatidylcholine (LPC) is derived from phosphatidylcholine by the action of enzyme phospholipase A2.
18:1-d7 Lyso PC has been used:
- as an internal standard in high performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC-ESIMS/MS) for the lipidomics analysis of bone marrow-derived macrophages
- as a component of extraction solvent for lipid isolation from biological samples
- as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)
Lysophosphatidylcholine (LPC). Elevated levels of LPC is associated with diabetes and cardiovascular diseases. LPC stimulates cytokines and is implicated in allergic disease. It also elicits lysis on membranes.
5 mL Clear Glass Sealed Ampule (791643C-1mg)
LIPIDOMIX is a registered trademark of Avanti Polar Lipids, Inc.
SPLASH is a registered trademark of Avanti Polar Lipids, Inc.