810288P

Avanti

16:0 TopFluor® cholesterol

23-(dipyrrometheneboron difluoride)-24-norcholesteryl palmitate, powder

Empirical Formula (Hill Notation):
C52H81 BF2N2O2
CAS Number:
Molecular Weight:
815.02
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810288P-1mg)

manufacturer/tradename

Avanti Polar Lipids 810288P

shipped in

dry ice

storage temp.

−20°C

General description

16:0 TopFluor® cholesterol carries saturated acyl chains. Approximately 30-40% of the mammalian plasma membrane consists of cholesterol. TopFluor® has a moiety, called dipyrromethene boron difluoride. This fluorescent molecule is covalently attached to various lipid molecules.

Application

16:0 TopFluor® cholesterol may be used to study its diffusion with phospholipid analogs in model membrane in order to understand cholesterol dynamics at the nanoscale in biomembranes.

Biochem/physiol Actions

Cholesterol participates in various signaling processes. It also helps in shaping the structure of molecular membrane.

Packaging

5 mL Amber Glass Screw Cap Vial (810288P-1mg)

Legal Information

TopFluor is a registered trademark of Avanti Polar Lipids, Inc.

storage_class_code

13 - Non Combustible Solids

Certificate of Analysis

Certificate of Origin

Nanoscale dynamics of cholesterol in the cell membrane
Pinkwart K, et al.
The Journal of biological chemistry, 294(34), 12599-12609 (2019)
Investigation of the biophysical properties of a fluorescently modified ceramide-1-phosphate
Shirey CM, et al.
Chemistry and Physics of Lipids, 200, 32-32 (2016)

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