850325C

Avanti

10:0 PC

1,2-didecanoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(s):
1,2-dicapryl-sn-glycero-3-phosphocholine; PC(10:0/10:0)
Empirical Formula (Hill Notation):
C28H56NO8P
CAS Number:
Molecular Weight:
565.72
NACRES:
NA.25
Pricing and availability is not currently available.

assay

>99% (TLC)

packaging

pkg of 1 × 2.5 mL (850325C-25mg)
pkg of 2 × 4 mL (850325C-200mg)

mfr. no.

Avanti Polar Lipids, 850325C

concentration

10 mg/mL (850325C-25mg)
25 mg/mL (850325C-200mg)

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3

InChI key

MLKLDGSYMHFAOC-UHFFFAOYSA-N

General description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

10:0 PC is suitable for use in the preparation of lipid bilayer samples.

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Packaging

5 mL Clear Glass Sealed Ampule (850325C-200mg)
5 mL Clear Glass Sealed Ampule (850325C-25mg)

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Target Organs

Central nervous system

RIDADR

UN 1888 6.1 / PGIII

WGK Germany

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificate of Analysis
Certificate of Origin
Integrative Medicine - E-Book (2017)
The Membranes of Cells (2016)
Tilt angle of a trans-membrane helix is determined by hydrophobic mismatch
Park SH and Opella SJ
Journal of molecular biology, 350(2), 310-318 (2005)
Efficacy of injections of phosphatidylcholine into fat deposits-a non-surgical alternative to liposuction in body-contouring
Karl GH, et al.
Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India, 38(2), 119-119 (2005)
Chun-Cheih Chao et al.
Cell, 179(7), 1483-1498 (2019-12-10)
Metabolism has been shown to control peripheral immunity, but little is known about its role in central nervous system (CNS) inflammation. Through a combination of proteomic, metabolomic, transcriptomic, and perturbation studies, we found that sphingolipid metabolism in astrocytes triggers the...
Articles
The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn
Read More

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.