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850370P

Avanti

21:0 PC

1,2-diheneicosanoyl-sn-glycero-3-phosphocholine, powder

Synonym(s):
PC(21:0/21:0)
Empirical Formula (Hill Notation):
C50H100NO8P
CAS Number:
Molecular Weight:
874.30
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (850370P-200mg)
pkg of 1 × 25 mg (850370P-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCCCCC)=O)=O

General description

Phosphatidylcholines (PCs) are phospholipids, that are ubiquitously present in the tissues of animals. The sn-1 and sn-2 position of PC has saturated and unsaturated fatty acids respectively. It can be produced through methylation pathway.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

21:0 PC has been used as a standard in linearity experiment to evaluate linearity response of the most abundant lipid classes. 21:0 PC may be used as an internal standard for the quantification of phospholipids (PLs). It may also be used as a phospholipid standard for the analysis of dried lipid extracts of S. meliloti in the positive-ionization mode.

Biochem/physiol Actions

Phosphatidylcholine (PC) helps to block the penetrance of bacteria by acting as a surfactant in the mucus.

Packaging

5 mL Amber Glass Screw Cap Vial (850370P-25mg)
5 mL Amber Glass Screw Cap Vial (850370P-200mg)

Storage Class Code

13 - Non Combustible Solids

Certificate of Analysis

Certificate of Origin

Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
Essentials of Medical Biochemistry, 299-320 (2015)
Libia Saborido Basconcillo et al.
Journal of lipid research, 50(6), 1120-1132 (2008-12-20)
A shotgun lipidomics approach that allowed the analysis of eight lipid classes directly from crude extracts of the soil bacterium Sinorhizobium meliloti is presented. New MS-MS transitions are reported for the analysis of monomethylphosphatidylethanolamines, dimethylphosphatidylethanolamines, and three bacterial non-phosphorus-containing lipid...
Alena Janovská et al.
American journal of physiology. Endocrinology and metabolism, 298(4), E779-E786 (2010-01-21)
A high-saturated-fat diet (HFD) induces obesity and insulin resistance (IR). IR has been linked to alterations and increased saturation in the phospholipid composition of skeletal muscles. We aimed to determine whether HFD feeding affects fatty acid (FA) membrane profile in...
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Kevin Huynh et al.
Cell chemical biology, 26(1), 71-84 (2018-11-13)
High-throughput targeted lipid profiling with liquid chromatography-mass spectrometry (LC-MS) has been used extensively to identify associations between plasma lipid species and disease states. Such methods, used to characterize larger clinical cohorts, often suffer from an inability to differentiate isomeric forms...

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