850456P

Avanti

16:0-18:0 PC

1-palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine, powder

Synonym(s):
1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine; PSPC; PC(16:0/18:0)
Empirical Formula (Hill Notation):
C42H84NO8P
CAS Number:
Molecular Weight:
762.09
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850456P-1g)
pkg of 1 × 25 mg (850456P-25mg)
pkg of 1 × 500 mg (850456P-500mg)

manufacturer/tradename

Avanti Polar Lipids 850456P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

General description

Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the tissues of the animal. 16:0-18:0 PC (PSPC/1-palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine) is a saturated lipid , which consists of two additional methylene units in the sn-2 acyl chain.

Application

16:0-18:0 PC (1-palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine) has been used in liposome preparation. It may be used as a phospholipid standard.

Biochem/physiol Actions

Phosphatidylcholines (PCs) play a functional role in reducing the level of blood lipid and cholesterol.

Packaging

20 mL Clear Glass Screw Cap Vial (850456P-500mg)
5 mL Amber Glass Screw Cap Vial (850456P-25mg)
20 mL Clear Glass Screw Cap Vial (850456P-1g)

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Joseph A Hankin et al.
Journal of the American Society for Mass Spectrometry, 18(9), 1646-1652 (2007-07-31)
Common organic matrix-assisted laser desorption/ionization (MALDI) matrices, 2,5-dihydroxybenzoic acid, 3,5-dimethoxy-4-hydroxycinnamic acid, and alpha-cyano-4-hydroxycinnamic acid, were found to undergo sublimation without decomposition under conditions of reduced pressure and elevated temperature. This solid to vapor-phase transition was exploited to apply MALDI matrix...
Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
Essentials of Medical Biochemistry, 299-320 (2015)
German Stepanov et al.
FEBS letters, 583(1), 97-100 (2008-12-09)
We attempted to evaluate the affinity of the anionic phospholipids to cytochrome c by means of surface plasmon resonance (SPR) technique and to correlate it with the cytochrome c active site alterations and peroxidase activity. Our experiments showed a strong...
Miao-Miao Zhou et al.
Lipids in health and disease, 15(1), 135-135 (2016-08-26)
Phosphatidylcholine (PC), the major source of dietary choline, has been demonstrated to improve the capability of learning and memory in rodent and the amelioration of long-chain n-3 polyunsaturated fatty acids (PUFA) on anti-aging and anti-oxidation is widely known as well....
Simon Becher et al.
Analytical chemistry, 90(19), 11486-11494 (2018-09-11)
Phosphatidylcholines are the major phospholipid component of most eukaryotic cell membranes. Phosphatidylcholines have been shown to actively participate in regulatory and metabolic processes. Dysfunctional metabolic processes have been linked to human disease and can result in altered phosphatidylcholine structural features...

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