850699P

Avanti

08:0 PE

1,2-dioctanoyl-sn-glycero-3-phosphoethanolamine, powder

Synonym(s):
PE(8:0/8:0)
Empirical Formula (Hill Notation):
C21H42NO8P
CAS Number:
Molecular Weight:
467.53
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (850699P-10mg)
pkg of 1 × 25 mg (850699P-25mg)

manufacturer/tradename

Avanti Polar Lipids 850699P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O

General description

Phosphatidylethanolamine (PE) is a glycerophospholipid. This nonbilayer-forming phospholipid has a cone shape due to the presence of its head group.

Application

08:0 PE (1,2-dioctanoyl-sn-glycero-3-phosphoethanolamine) may be used in the preparation of DOPC liposomes for pH sensor conjugation in imaging pH changes in living cells.

Biochem/physiol Actions

Phosphatidylethanolamine (PE) plays a vital role in the structure and function of eukaryotic membranes. It serves as a lipid chaperon. It is known to participate in the initiation of autophagy. The hexagonal phase of PE is involved in membrane fusion events.

Packaging

5 mL Clear Glass Sealed Ampule (850699P-25mg)
5 mL Clear Glass Sealed Ampule (850699P-10mg)

storage_class_code

13 - Non Combustible Solids

Certificate of Analysis

Certificate of Origin

Jungju Yoon et al.
Advanced materials (Deerfield Beach, Fla.), 26(26), 4559-4564 (2014-05-03)
Phase separation in films of phospholipids and conjugated polymers results in nanoassemblies because of a difference in the physicochemical properties between the hydrophobic polymers and the polar lipid heads, together with the comparable polymer side-chain lengths to lipid tail lengths...
Ronja Marie Kühnel et al.
The Analyst, 144(9), 3030-3037 (2019-03-23)
The design of ion sensors has gained importance for the study of ion dynamics in cells, with fluorescent proton nanosensors attracting particular interest because of their applicability in monitoring pH gradients in biological microcompartments and reconstituted membrane systems. In this...
Federica Gibellini et al.
IUBMB life, 62(6), 414-428 (2010-05-27)
The glycerophospholipids phosphatidylcholine (PC) and phosphatidylethanolamine (PE) account for greater than 50% of the total phospholipid species in eukaryotic membranes and thus play major roles in the structure and function of those membranes. In most eukaryotic cells, PC and PE...
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial...

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