850700P

Avanti

10:0 PE

1,2-didecanoyl-sn-glycero-3-phosphoethanolamine, powder

Synonym(s):
PE(10:0/10:0)
Empirical Formula (Hill Notation):
C25H50NO8P
CAS Number:
Molecular Weight:
523.64
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (850700P-25mg)

manufacturer/tradename

Avanti Polar Lipids 850700P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O

General description

Phosphatidylethanolamine is an aminophospholipid, which is found in eukaryotic and prokaryotic cells. It is one of the most abundant glycerophospholipids in the biological membranes. Phosphatidylethanolamine is found in nervous tissue.

Application

10:0 PE has been used for the synthesis of fluorescent phospholipid derivative NBD-didecanoylphosphatidylethanolamine (NBD-diC10PE).

Biochem/physiol Actions

Phosphatidylethanolamine forms pure lipid structures. It maintains membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a critical role in autophagy, cell division and protein folding. It acts as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine functions as an intermediate for the synthesis of glycerophospholipid classes.

Packaging

5 mL Clear Glass Sealed Ampule (850700P-25mg)

storage_class_code

13 - Non Combustible Solids

Certificate of Analysis

Certificate of Origin

The Membranes of Cells (2016)
Binding of phospholipids to beta-Lactoglobulin and their transfer to lipid bilayers
Martins PAT, et al.
Biochimica et Biophysica Acta - Biomembranes, 1778(5), 1308-1315 (2008)
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1831, 543-554 (2013)
An Introduction to Biological Membranes: Composition, Structure and Function (2016)
Phosphatidylethanolamine is a key regulator of membrane fluidity in eukaryotic cells
Dawaliby R, et al.
The Journal of Biological Chemistry, 291(7), 3658-3667 (2016)

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