All Photos(2)

850700P

Avanti

10:0 PE

1,2-didecanoyl-sn-glycero-3-phosphoethanolamine, powder

Synonym(s):
PE(10:0/10:0)
Empirical Formula (Hill Notation):
C25H50NO8P
CAS Number:
Molecular Weight:
523.64
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (850700P-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O

General description

Phosphatidylethanolamine is an aminophospholipid, which is found in eukaryotic and prokaryotic cells. It is one of the most abundant glycerophospholipids in the biological membranes. Phosphatidylethanolamine is found in nervous tissue.

Application

10:0 PE has been used for the synthesis of fluorescent phospholipid derivative NBD-didecanoylphosphatidylethanolamine (NBD-diC10PE).

Biochem/physiol Actions

Phosphatidylethanolamine forms pure lipid structures. It maintains membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a critical role in autophagy, cell division and protein folding. It acts as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine functions as an intermediate for the synthesis of glycerophospholipid classes.

Packaging

5 mL Clear Glass Sealed Ampule (850700P-25mg)

Storage Class Code

13 - Non Combustible Solids

Certificate of Analysis

Certificate of Origin

Binding of phospholipids to beta-Lactoglobulin and their transfer to lipid bilayers
Martins PAT, et al.
Biochimica et Biophysica Acta - Biomembranes, 1778(5), 1308-1315 (2008)
An Introduction to Biological Membranes: Composition, Structure and Function (2016)
The Membranes of Cells (2016)
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1831, 543-554 (2013)
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei
Farine L, et al.
Scientific reports, 5, 16787-16787 (2015)

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