850757C

Avanti

16:0-18:1 PE

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine, chloroform

Synonym(s):
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; POPE; PE(16:0/18:1(9Z)); 110637
Empirical Formula (Hill Notation):
C39H76NO8P
CAS Number:
Molecular Weight:
718.00
NACRES:
NA.25

assay

>99% (TLC)

packaging

pkg of 1 × 2.5 mL (850757C-25mg)
pkg of 2 × 20 mL (850757C-1g)
pkg of 2 × 4 mL (850757C-200mg)
pkg of 5 × 4 mL (850757C-500mg)

manufacturer/tradename

Avanti Polar Lipids 850757C

concentration

10 mg/mL (850757C-25mg)
25 mg/mL (850757C-1g)
25 mg/mL (850757C-200mg)
25 mg/mL (850757C-500mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17-

InChI key

FHQVHHIBKUMWTI-ZCXUNETKSA-N

Application

16:0-18:1 PE has been used as a synthetic lipid for the preparation of liposomes.

Packaging

5 mL Clear Glass Sealed Ampule (850757C-200mg)
5 mL Clear Glass Sealed Ampule (850757C-500mg)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850757C-1g)
5 mL Clear Glass Sealed Ampule (850757C-25mg)

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

hazcat

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

storage_class_code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Mitochondria: Practical Protocols (2018)
Ionization Properties of Phospholipids Determined by Zeta Potential Measurements
Sathappa M and Alder NN
Bio-protocol, 6(22) (2016)
Mariya Chavarha et al.
Langmuir : the ACS journal of surfaces and colloids, 28(48), 16596-16604 (2012-11-13)
Prior studies have shown that the biological mixture of the two hydrophobic surfactant proteins, SP-B and SP-C, produces faster adsorption of the surfactant lipids to an air/water interface, and that they induce 1-palmitoyl-2-oleoyl phosphatidylethanolamine (POPE) to form inverse bicontinuous cubic...
Sónia Troeira Henriques et al.
Journal of the American Chemical Society, 141(51), 20460-20469 (2019-11-26)
Peptides with pharmaceutical activities are attractive drug leads, and knowledge of their mode-of-action is essential for translation into the clinic. Comparison of native and enantiomeric peptides has long been used as a powerful approach to discriminate membrane- or receptor-mediated modes-of-action...
Charles G Cranfield et al.
Langmuir : the ACS journal of surfaces and colloids, 33(26), 6630-6637 (2017-06-14)
Cyclotides are cyclic disulfide-rich peptides that are chemically and thermally stable and possess pharmaceutical and insecticidal properties. The activities reported for cyclotides correlate with their ability to target phosphatidylethanolamine (PE)-phospholipids and disrupt cell membranes. However, the mechanism by which this...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service