850759C

Avanti

16:0-20:4 PE

1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine, chloroform

Synonym(s):
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine; PAPE; PE(16:0/20:4(5Z,8Z,11Z,14Z)); 110638
Empirical Formula (Hill Notation):
C41H74NO8P
CAS Number:
Molecular Weight:
740.00
NACRES:
NA.25

assay

>99% (TLC)

packaging

pkg of 1 × 2.5 mL (850759C-25mg)

manufacturer/tradename

Avanti Polar Lipids 850759C

concentration

10 mg/mL (850759C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

Application

16:0-20:4 PE has been used to determine its effect on oxidative burst in neutrophil granulocytes. It has also been used to determine its detergent solubility with equimolar concentration of sphingomyelin/cholesterol (SM/CHOL).

Packaging

5 mL Clear Glass Sealed Ampule (850759C-25mg)

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

hazcat

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

storage_class_code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK Germany

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificate of Analysis

Certificate of Origin

The oxidation state of phospholipids controls the oxidative burst in neutrophil granulocytes
Bluml S, et al.
Journal of Immunology, 181(6), 4347-4353 (2008)
Acyl chain unsaturation in PEs modulates phase separation from lipid raft molecules
Shaikh SR, et al.
Biochemical and Biophysical Research Communications, 311(3), 793-796 (2003)
Bruna Neves et al.
Molecules (Basel, Switzerland), 25(9) (2020-05-07)
Nitrated phospholipids have recently been detected in vitro and in vivo and associated with beneficial health effects. They were identified and quantified in biological samples by lipidomics methodologies using liquid chromatography-collision-induced dissociation (CID) tandem mass spectrometry (MS/MS) acquired with the...

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