855375P

10:0 Lyso PC

1-decanoyl-2-hydroxy-sn-glycero-3-phosphocholine, powder

• Synonym(s): 1-decanoyl-sn-glycero-3-phosphocholine; PC(10:0/0:0)
• Empirical Formula (Hill Notation): C₁₈H₃₈NO₇P
• CAS Number: 22248-63-1
• Molecular Weight: 411.47

Properties

• assay: >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
• form: powder
• packaging: pkg of 1 × 25 mg (855375P-25mg); pkg of 1 × 500 mg (855375P-500mg)
• manufacturer/tradename: Avanti Polar Lipids 855375P
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCC)=O

Description

General description

Lyso-phosphatidylcholine (LPC) is a bioactive proinflammatory lipid secreted on pathological response. It has a choline group at its polar head.

Application

10:0 Lyso PC has been used as an internal standard to quantify the most abundant lysophosphatidylcholine (LPC) species found in Trypanosoma cruzi samples.

Biochem/physiol Actions

Lysophosphatidylcholine (LPC) alters various biological functions in different cell-types, such as endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC activates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.

Packaging

5 mL Clear Glass Sealed Ampule (855375P-25mg)

20 mL Clear Glass Screw Cap Vial (855375P-500mg)

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable