855725C

Avanti

2-18:1 Lyso PE

1-Hydroxy-2-oleoyl-sn-glycero-3-phosphoethanolamine, chloroform solution

Empirical Formula (Hill Notation):
C23H46NO7P
CAS Number:
Molecular Weight:
479.59
NACRES:
NA.25

assay

>99% (TLC)

form

chloroform solution

packaging

pkg of 1 × 1 mL (855725C-10MG)
pkg of 1 × 1 mL (855725C-1MG)
pkg of 1 × 1 mL (855725C-5MG)

manufacturer/tradename

Avanti Polar Lipids

concentration

1 mg/mL in chloroform (855725C-1MG)
10 mg/mL in chloroform (855725C-10MG)
5 mg/mL in chloroform (855725C-5MG)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[NH3+])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO)=O

General description

2-18:1 Lyso PE is a lyso phosphatidylethanolamine with oleic acid substitution at sn-2 position. LPE is synthesized from phosphatidylethanolamine (PE) through the action of phospholipase A.

Application

2-18:1 Lyso PE is suitable for use as standard, as sn-2 isomers of lyso PE for hydrophilic interaction liquid chromatography-paired with ion mobility-mass spectrometry (HILIC-IM-MS), and high performance thin-layer chromatography (HPTLC).

Biochem/physiol Actions

Lyso phosphatidylethanolamine (Lyso PE) is a lipid present naturally in plants and it retards senescence in leaves, postharvest fruits and flowers. LPE has antifungal and antibacterial activity. LPE functions to induce neuronal differentiation, increases intracellular calcium, stimulates chemotactic migration and cellular invasion in cancer cells.

Packaging

5 mL Clear Glass Sealed Ampule (855725C-1MG, 855725C-5MG, and 855725C-10MG)

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

hazcat

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

storage_class_code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Trypanosoma cruzi epimastigotes store cholesteryl esters in lipid droplets after cholesterol endocytosis.
Pereira MG, et al.
Molecular and Biochemical Parasitology, 224, 6-16 (2018)
Inhibition of phospholipase D by lysophosphatidylethanolamine, a lipid-derived senescence retardant.
Ryu SB, et al.
Proceedings of the National Academy of Sciences of the USA, 94(23), 12717-12721 (1997)
Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine and lysophosphatidylglycerol.
Makide K, et al.
Prostaglandins & other lipid mediators, 89(3-4), 135-139 (2009)
Lipidomic consequences of phospholipid synthesis defects in Escherichia coli revealed by HILIC-ion mobility-mass spectrometry.
Hines KM and Xu L
Chemistry and Physics of Lipids, 219, 15-22 (2019)

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