856705P

Avanti

16:0 Lyso PE

1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine, powder

Synonym(s):
1-hexadecanoyl-sn-glycero-3-phosphoethanolamine; PE(16:0/0:0); 110698
Empirical Formula (Hill Notation):
C21H44NO7P
CAS Number:
Molecular Weight:
453.55
NACRES:
NA.25

assay

>99% (LPE; may contain up to 10% of the 2-LPE isomer, TLC)

form

powder

packaging

pkg of 1 × 200 mg (856705P-200mg)
pkg of 1 × 25 mg (856705P-25mg)

manufacturer/tradename

Avanti Polar Lipids 856705P

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[NH3+])=O)([H])COC(CCCCCCCCCCCCCCC)=O

Application

16:0 Lyso PE has been used to degranulate human eosinophils. It has also been used to enhance nerve growth factor (NGF)-induced mitogen-activated protein kinase (MAPK) phosphorylation.

Packaging

5 mL Amber Glass Screw Cap Vial (856705P-200mg)
5 mL Amber Glass Screw Cap Vial (856705P-25mg)

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Lysophosphatidylcholine enhances NGF-induced MAPK and Akt signals through the extracellular domain of TrkA in PC12 cells
Itakura A, et al.
FEBS Open Bio, 3(1), 243-251 (2013)
Yoko Shima et al.
The Journal of biological chemistry, 295(20), 6983-6991 (2020-04-10)
Newly synthesized major histocompatibility complex (MHC) class I proteins are stabilized in the endoplasmic reticulum (ER) by binding 8-10-mer-long self-peptide antigens that are provided by transporter associated with antigen processing (TAP). These MHC class I:peptide complexes then exit the ER...
Miki Eto et al.
International journal of molecular sciences, 13(12), 16267-16280 (2012-12-05)
Cellular membranes contain glycerophospholipids, which have important structural and functional roles in cells. Glycerophospholipids are first formed in the de novo pathway (Kennedy pathway) and are matured in the remodeling pathway (Lands' cycle). Recently, lysophospholipid acyltransferases functioning in Lands' cycle...
Qingxin Shi et al.
Food & function, 10(12), 7782-7792 (2019-11-30)
Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple...
Kimberly D Dyer et al.
Journal of immunology (Baltimore, Md. : 1950), 184(11), 6327-6334 (2010-04-28)
Platelet-activating factor (PAF [1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine]) is a phospholipid mediator released from activated macrophages, mast cells, and basophils that promotes pathophysiologic inflammation. Eosinophil responses to PAF are complex and incompletely elucidated. We show in this article that PAF and its 2-deacetylated metabolite...

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